Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX1 | Q9Y5S8 | 12/20 | 0.65 |
| ▸ | GAA | P10253 | 7/20 | 0.65 |
| ▸ | MAPT | P10636 | 7/20 | 0.65 |
| ▸ | MEN1 | O00255 | 5/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.65 |
| ▸ | SNCA | P37840 | 3/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.65 |
| ▸ | BCHE | P06276 | 2/20 | 0.65 |
| ▸ | ACHE | P22303 | 2/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.65 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.65 |
| ▸ | MAOA | P21397 | 1/20 | 0.65 |
| ▸ | CNR1 | P21554 | 1/20 | 0.65 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.65 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.65 |
| ▸ | HTR2C | P28335 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL299552 | 0.89 | NOX1 (0.65) | NOX1GAAMAPTMEN1KMT2A | |
| Phenothiazine SCHEMBL7768973 | 0.88 | NOX1 (0.77) | NOX1GAAMAPTMEN1KMT2A | |
| SCHEMBL29499615 | 0.86 | MAOA (0.49) | NOX1GAAMAPTMEN1KMT2A | |
| SCHEMBL27581232 | 0.86 | MAOA (0.49) | NOX1GAAMAPTMEN1KMT2A | |
| Phenothiazine SCHEMBL27756460 | 0.86 | NOX1 (0.74) | NOX1GAAMAPTMEN1KMT2A | |
| Phenothiazine SCHEMBL4937245 | 0.83 | NOX1 (0.94) | NOX1GAAMAPTMEN1KMT2A | |
| Phenothiazine SCHEMBL22584033 | 0.82 | NOX1 (0.74) | NOX1GAAMAPTMEN1KMT2A | |
| Phenothiazine SCHEMBL2504207 | 0.81 | NOX1 (1.00) | NOX1GAAMAPTMEN1KMT2A | |
| Phenothiazine SCHEMBL6315328 | 0.81 | NOX1 (1.00) | NOX1GAAMAPTMEN1KMT2A | |
| Phenothiazine SCHEMBL9114 | 0.81 | NOX1 (1.00) | NOX1GAAMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10947328-B2 | Polymer comprising a plurality of phenothiazine groups and methods of making the same | ASCENSIA DIABETES CARE HOLDINGS AG (CH) | 2021-03-16 | — | — | US | disclosed |
| US-20200255552-A1 | POLYMER COMPRISING A PLURALITY OF PHENOTHIAZINE GROUPS AND METHODS OF MAKING THE SAME | ASCENSIA DIABETES CARE HOLDINGS AG (CH) | 2020-08-13 | — | — | US | disclosed |
| US-10662264-B2 | Polymer comprising a plurality of phenothiazine groups and methods of making the same | ASCENSIA DIABETES CARE HOLDINGS AG (CH) | 2020-05-26 | — | — | US | disclosed |
| CN-110317198-A | A kind of phenothiazine compounds and its preparation method and application | 信阳师范学院 | 2019-10-11 | — | — | CN | disclosed |
| US-20180194877-A1 | POLYMER COMPRISING A PLURALITY OF PHENOTHIAZINE GROUPS AND METHODS OF MAKING THE SAME | BAYER HEALTHCARE LLC | 2018-07-12 | — | — | US | disclosed |
| US-9944725-B2 | Polymer comprising a plurality of phenothiazine groups and methods of making the same | ASCENSIA DIABETES CARE HOLDINGS AG (CH) | 2018-04-17 | — | — | US | disclosed |
| US-20170044276-A1 | POLYMER COMPRISING A PLURALITY OF PHENOTHIAZINE GROUPS AND METHODS OF MAKING THE SAME | BAYER HEALTHCARE LLC | 2017-02-16 | — | — | US | disclosed |
| US-9505884-B2 | Polymer comprising a plurality of phenothiazine groups and methods of making the same | ASCENSIA DIABETES CARE HOLDINGS AG (CH) | 2016-11-29 | — | — | US | disclosed |
| US-20160083519-A1 | Polymer Comprising A Plurality Of Phenothiazine Groups And Methods Of Making The Same | ASCENSIA DIABETES CARE HOLDINGS AG (CH) | 2016-03-24 | — | — | US | disclosed |
| US-9238717-B2 | Polymer comprising a plurality of phenothiazine groups and methods of making the same | BAYER HEALTHCARE LLC (US) | 2016-01-19 | — | — | US | disclosed |
| US-6809090-B2 | NITROGEN MONOXIDE SYNTHASE AND/OR LIPIDIC PEROXIDATION INHIBITORS | IPSEN PHARMA S.A.S. (FR) | 2004-10-26 | — | — | US | disclosed |
| US-20040097494-A1 | New derivatives of N-(iminomethy)amines, their preparation, their use as medicaments and the pharmaceutical compositions containing them | SOCIETE DE CONSEILS DE RECHERCHES D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) | 2004-05-20 | — | — | US | disclosed |
| CN-1144799-C | N-(iminomethyl) amine derivatives, their preparation, their use as medicines and compositions containing them | ��ѧ�о���Ӧ����ѯ��˾ | 2004-04-07 | — | — | CN | disclosed |
| US-6620840-B1 | Nitric oxide synthase inhibitors | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2003-09-16 | — | — | US | disclosed |
| US-6482822-B1 | N-(iminomethyl)amines derivatives, their preparation, their use as medicines and compositions containing them | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2002-11-19 | — | — | US | disclosed |
| CN-1335841-A | N- (iminomethyl) amine derivatives, their preparation, their use as medicaments and pharmaceutical compositions containing them | SOD CONSEILS RECH APPLIC (FR) | 2002-02-13 | — | — | CN | disclosed |
| EP-1115720-A2 | NOVEL N-(IMINOMETHYL)AMINE DERIVATIVES, THEIR PREPARATION, THEIR USE AS MEDICINES AND COMPOSITIONS CONTAINING THEM | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2001-07-18 | — | — | EP | disclosed |
| WO-2000017191-A2 | N-(IMINOMETHYL)AMINE DERIVATIVES, THEIR PREPARATION, THEIR USE AS MEDICINES AND COMPOSITIONS CONTAINING THEM | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2000-03-30 | — | — | WO | disclosed |
| US-5756356-A | COLORIMETRIC | TOYO INK MANUFACTURING CO., LTD. (JP) | 1998-05-26 | — | — | US | disclosed |
| EP-0735368-A1 | Method of indicating time or temperature-time accumulated value as color change, and materials therefor | TOYO INK MANUFACTURING CO., LTD. (JP) | 1996-10-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200255552-A1 | POLYMER COMPRISING A PLURALITY OF PHENOTHIAZINE GROUPS AND METHODS OF MAKING THE SAME | PAH, TYK2, PNMT | NOX1 2861/4885GAA 380/4885MAPT 178/4885 |
| US-20160083519-A1 | Polymer Comprising A Plurality Of Phenothiazine Groups And Methods Of Making The Same | PAH, TYK2, PNMT | NOX1 2861/4885GAA 380/4885MAPT 178/4885 |
| US-20040097494-A1 | New derivatives of N-(iminomethy)amines, their preparation, their use as medicaments and the pharmaceutical compositions containing them | NOS1, NOS2, NOS3 | NOX1 8/4885GAA 1464/4885MAPT 629/4885 |
| US-20180194877-A1 | POLYMER COMPRISING A PLURALITY OF PHENOTHIAZINE GROUPS AND METHODS OF MAKING THE SAME | PAH, TYK2, PNMT | NOX1 2861/4885GAA 380/4885MAPT 178/4885 |
| US-10947328-B2 | Polymer comprising a plurality of phenothiazine groups and methods of making the same | PAH, TYK2, PNMT | NOX1 2861/4885GAA 380/4885MAPT 178/4885 |
| US-20170044276-A1 | POLYMER COMPRISING A PLURALITY OF PHENOTHIAZINE GROUPS AND METHODS OF MAKING THE SAME | PAH, TYK2, PNMT | NOX1 2861/4885GAA 380/4885MAPT 178/4885 |
| US-10662264-B2 | Polymer comprising a plurality of phenothiazine groups and methods of making the same | PAH, TYK2, PNMT | NOX1 2861/4885GAA 380/4885MAPT 178/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.