SCHEMBL299552

SCHEMBL299552

Oc1ccc2c(c1)Sc1ccccc1N2

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOX1 Q9Y5S8 11/20 0.65
MAPT P10636 7/20 0.65
GAA P10253 6/20 0.65
MEN1 O00255 4/20 0.65
KMT2A Q03164 4/20 0.65
SNCA P37840 4/20 0.65
TDP1 Q9NUW8 2/20 0.65
BCHE P06276 2/20 0.65
ACHE P22303 2/20 0.65
ALOX15 P16050 2/20 0.65
MAOA P21397 2/20 0.65
CYP1A2 P05177 1/20 0.65
POLB P06746 1/20 0.65
CYP3A4 P08684 1/20 0.65
ADORA3 P0DMS8 1/20 0.65
ALOX12 P18054 1/20 0.65
CNR1 P21554 1/20 0.65
PTGS1 P23219 1/20 0.65
SLC6A2 P23975 1/20 0.65
HTR2C P28335 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8941074 0.90 MAOA (0.55) NOX1MAPTGAAMEN1KMT2A
SCHEMBL2720811 0.89 NOX1 (0.65) NOX1MAPTGAAMEN1KMT2A
Phenothiazine SCHEMBL7768973 0.88 NOX1 (0.77) NOX1MAPTGAAMEN1KMT2A
SCHEMBL29499615 0.86 MAOA (0.49) NOX1MAPTGAAMEN1KMT2A
SCHEMBL27581232 0.86 MAOA (0.49) NOX1MAPTGAAMEN1KMT2A
Phenothiazine SCHEMBL27756460 0.86 NOX1 (0.74) NOX1MAPTGAAMEN1KMT2A
Phenothiazine SCHEMBL22584033 0.82 NOX1 (0.74) NOX1MAPTGAAMEN1KMT2A
Phenothiazine SCHEMBL9114 0.81 NOX1 (1.00) NOX1MAPTGAAMEN1KMT2A
Phenothiazine SCHEMBL2504207 0.81 NOX1 (1.00) NOX1MAPTGAAMEN1KMT2A
Phenothiazine SCHEMBL6315328 0.81 NOX1 (1.00) NOX1MAPTGAAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 273 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118324975-A Phenothiazine skeleton macromolecule cationic photoinitiator and preparation method and application thereof 江南大学 2024-07-12 CN claimed
CN-118324975-A Phenothiazine skeleton macromolecule cationic photoinitiator and preparation method and application thereof 江南大学 2024-07-12 CN disclosed
EP-3488868-B1 PHARMACEUTICAL COMPOSITION FOR ORAL ADMINISTRATION CONTAINING SULFASALAZINE AND / OR A SULFASALAZINE ORGANIC SALT, PRODUCTION PROCESS AND USE MEDAC GES FUER KLINISCHE SPEZIALPRAEPARATE MBH (DE) 2023-09-13 EP disclosed
US-11690857-B2 Pharmaceutical composition for oral administration containing sulfasalazine and/or a sulfasalazine organic salt, production process and use MEDAC GESELLSCHAFT FUER KLINISCHE SPEZIALPRAEPARATE MBH 2023-07-04 US disclosed
US-20210369743-A1 PHARMACEUTICAL COMPOSITION FOR ORAL ADMINISTRATION CONTAINING SULFASALAZINE AND/OR A SULFASALAZINE ORGANINC SALT, PRODUCTION PROCESS AND USE MEDAC GESELLSCHAFT FUER KLINISCHE SPEZIALPRAEPARATE MBH (DE) 2021-12-02 US disclosed
CN-109467561-B Double-donor hole transport material containing phenothiazine structure, preparation method thereof and perovskite solar cell 广东工业大学 2021-07-02 CN disclosed
EP-3713605-A1 PHARMACEUTICAL COMPOSITION FOR ORAL ADMINISTRATION CONTAINING SULFASALAZINE AND / OR A SULFASALAZINE ORGANIC SALT, PRODUCTION PROCESS AND USE medac Gesellschaft für klinische Spezialpräparate mbH (DE) 2020-09-30 EP disclosed
EP-3713918-A1 SULFASALAZINE SALTS, PRODUCTION PROCESSES AND USES medac Gesellschaft für klinische Spezialpräparate mbH (DE) 2020-09-30 EP disclosed
EP-3630188-A1 A PHARMACEUTICAL COMPOSITION COMPRISING A COMBINATION OF METHOTREXATE AND NOVOBIOCIN, AND THE USE OF SAID COMPOSITION IN THERAPY Truly Translational Sweden AB (SE) 2020-04-08 EP disclosed
EP-2751104-B1 COMPOUNDS AND COMPOSITIONS AS C-KIT KINASE INHIBITORS NOVARTIS AG (CH) 2019-09-25 EP disclosed
WO-2004087659-A1 CHEMICAL COMPOUNDS ASTRAZENECA AB (SE) 2004-10-14 WO disclosed
WO-2004085423-A1 PIPERIDINE DERIVATIVES FOR THE TREATMENT OF CHEMOKINE OR H1 MEDIATED DISEASE STATE ASTRAZENECA AB (SE) 2004-10-07 WO disclosed
US-5155148-A For stabilizing oxidizable rubbers, oils; co-polymerizable through unsaturated site THE GOODYEAR TIRE & RUBBER COMPANY (US) 1992-10-13 US disclosed
EP-0420790-A1 Ester derivatives from p-hydroxydiphenylamine THE GOODYEAR TIRE & RUBBER COMPANY (US) 1991-04-03 EP disclosed
EP-0106937-B1 PHENOTHIAZINE LEUCODYES FOR ELECTROCHROMIC RECORDING International Business Machines Corporation (US) 1987-09-23 EP disclosed
EP-0062257-B1 SULPHUR DYES, PROCESS FOR THEIR PREPARATION AND THEIR USE CASSELLA Aktiengesellschaft (DE) 1984-07-25 EP disclosed
EP-0106937-A2 Phenothiazine leucodyes for electrochromic recording International Business Machines Corporation (US) 1984-05-02 EP disclosed
US-4439280-A Phenothiazine leucodyes for electrochromic recording INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1984-03-27 US disclosed
US-4403995-A Sulphur dyestuffs, a process for their manufacture and their use from hydroxy-diphenylamine compounds CASSELLA AKTIENGESELLSCHAFT (DE) 1983-09-13 US disclosed
EP-0062257-A1 Sulphur dyes, process for their preparation and their use CASSELLA Aktiengesellschaft (DE) 1982-10-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210369743-A1 PHARMACEUTICAL COMPOSITION FOR ORAL ADMINISTRATION CONTAINING SULFASALAZINE AND/OR A SULFASALAZINE ORGANINC SALT, PRODUCTION PROCESS AND USE SI, ALPI, SOST NOX1 614/4885MAPT 3679/4885GAA 1285/4885
US-11690857-B2 Pharmaceutical composition for oral administration containing sulfasalazine and/or a sulfasalazine organic salt, production process and use SI, SOST, ALPI NOX1 849/4885MAPT 3526/4885GAA 633/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.