SCHEMBL7768993

SCHEMBL7768993

CCOC(=O)C(=O)ONC(=N)N

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.46
GAA P10253 2/20 0.41
MGAM O43451 1/20 0.41
SI P14410 1/20 0.41
MGAM2 Q2M2H8 1/20 0.41
EGLN1 Q9GZT9 1/20 0.39
ALDH1A1 P00352 5/20 0.39
MAPT P10636 2/20 0.38
NPSR1 Q6W5P4 1/20 0.38
GLO1 Q04760 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.37
CYP2D6 P10635 1/20 0.37
LMNA P02545 1/20 0.37
HSD17B10 Q99714 1/20 0.37
TSHR P16473 1/20 0.36
SOAT1 P35610 1/20 0.36
CAD P27708 1/20 0.34
CYP1A2 P05177 1/20 0.33
HTT P42858 1/20 0.33
TRPA1 O75762 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL508005 0.81 LMNA (0.32) ALDH1A1LMNATSHRCYP1A2
SCHEMBL15573953 0.80 ALDH1A1 (0.52) ALOX15GAAMGAMSIMGAM2
Water SCHEMBL9343736 0.78 TSHR (0.30) LMNATSHRCYP1A2
SCHEMBL10881755 0.77 TSHR (0.51) ALDH1A1MAPTNPSR1TSHR
SCHEMBL289464 0.77 GAA (0.44) ALOX15GAAMGAMSIMGAM2
SCHEMBL208479 0.77
SCHEMBL7262 0.75 ALDH1A1 (0.62) ALOX15GAAMGAMSIMGAM2
SCHEMBL1331989 0.75 ALDH1A1 (0.62) ALOX15GAAMGAMSIMGAM2
SCHEMBL9823358 0.75 ALDH1A1 (0.62) ALOX15GAAMGAMSIMGAM2
SCHEMBL15659309 0.75 GAA (0.46) ALOX15GAAMGAMSIMGAM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0890355-B1 Hair treatment composition KAO CORP (JP) 2001-05-30 EP disclosed
US-6071504-A GUANIDIUM SALT, AMINO-MODIFIED POLYSILOXANE; ODORLESS, SKIN SENSITIVITY KAO CORPORATION (JP) 2000-06-06 US disclosed
EP-0890355-A1 Hair treatment composition Kao Corporation (JP) 1999-01-13 EP disclosed