SCHEMBL289464

SCHEMBL289464

CCOC(=O)C(=O)ONN

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.44
ALOX15 P16050 1/20 0.44
MGAM O43451 1/20 0.44
SI P14410 1/20 0.44
MGAM2 Q2M2H8 1/20 0.44
EGLN1 Q9GZT9 1/20 0.42
ALDH1A1 P00352 6/20 0.42
MAPT P10636 2/20 0.41
LMNA P02545 1/20 0.40
HSD17B10 Q99714 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
GLO1 Q04760 1/20 0.40
SMN1; SMN2 Q16637 2/20 0.39
CYP2D6 P10635 1/20 0.39
TSHR P16473 1/20 0.39
SOAT1 P35610 1/20 0.39
KDM4E B2RXH2 1/20 0.36
TRPA1 O75762 1/20 0.36
CYP1A2 P05177 1/20 0.35
HTT P42858 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1777800 0.82 SMN1; SMN2 (0.39) GAAALDH1A1LMNASMN1; SMN2TSHR
SCHEMBL7262 0.79 ALDH1A1 (0.62) GAAALOX15MGAMSIMGAM2
SCHEMBL9823358 0.79 ALDH1A1 (0.62) GAAALOX15MGAMSIMGAM2
SCHEMBL1331989 0.79 ALDH1A1 (0.62) GAAALOX15MGAMSIMGAM2
SCHEMBL10840657 0.78
SCHEMBL7768993 0.77 ALOX15 (0.46) GAAALOX15MGAMSIMGAM2
Hydrazine SCHEMBL3999673 0.76 ALOX15 (0.55) GAAALOX15MGAMSIMGAM2
SCHEMBL9751764 0.76 ALDH1A1 (0.59) GAAALOX15MGAMSIMGAM2
SCHEMBL30076441 0.76 ALDH1A1 (0.59) GAAALOX15MGAMSIMGAM2
Ammonia Solution, Strong SCHEMBL12803984 0.76 ALDH1A1 (0.59) GAAALOX15MGAMSIMGAM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 287 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108746656-B Pre-alloyed powder for diamond products and preparation method thereof 威海职业学院 2021-11-26 CN claimed
US-20260027113-A1 PHTHALAZINONE BASED MODULATORS FOR THE TREATMENT OF DISEASE SOLEY THERAPEUTICS INC (US) 2026-01-29 US disclosed
EP-4680608-A1 2,6-DIHYDRO-7H-PYRAZOLO[3,4-C]PYRIDIN-7-ONE DERIVATIVES AS ANTI-MALARIAL AGENTS MMV Medicines for Malaria Venture (CH) 2026-01-21 EP disclosed
US-12465603-B2 Phthalazinone based modulators for the treatment of disease SOLEY THERAPEUTICS, INC. (US) 2025-11-11 US disclosed
EP-4619387-A1 PHTHALAZINONE BASED MODULATORS FOR THE TREATMENT OF DISEASE Soley Therapeutics, Inc. (US) 2025-09-24 EP disclosed
WO-2025077721-A1 MYT1 INHIBITOR BASED ON FUSED THIAZOLE OR PYRIDINE RING PHARMAENGINE, INC. (CN) 2025-04-17 WO disclosed
CN-114787155-B Pharmaceutical compounds 辉瑞公司 2025-02-28 CN disclosed
US-20240374589-A1 PHTHALAZINONE BASED MODULATORS FOR THE TREATMENT OF DISEASE SOLEY THERAPEUTICS, INC. 2024-11-14 US disclosed
WO-2024199260-A1 PYRAZOL-5-ETHER COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF 南通泰禾化工股份有限公司 2024-10-03 WO disclosed
CN-118702628-A Pyrazole-5-ether compound as well as preparation method and application thereof 南通泰禾化工股份有限公司 2024-09-27 CN disclosed
EP-0326873-A2 Teicoplanin hydrazides GRUPPO LEPETIT S.p.A. (IT) 1989-08-09 EP disclosed
US-4365062-A BACTERICIDAL ANTIBIOTICS RHONE-POULENC INDUSTRIES (FR) 1982-12-21 US disclosed
US-4307230-A ANTIBIOTICS RHONE-POULENC INDUSTRIES (FR) 1981-12-22 US disclosed
US-4307233-A ANTIBACTERIAL AGENTS RHONE-POULENC INDUSTRIES (FR) 1981-12-22 US disclosed
US-4307116-A BACTERICIDES RHONE-POULENC INDUSTRIES (FR) 1981-12-22 US disclosed
US-4195087-A BACTERICIDES, FEED ADDITIVES ABIC, LTD. (IL) 1980-03-25 US disclosed
US-4075222-A VETERINARY MEDICINE, BACTERICIDES, FUNGICIDES, ANTIPROTOZOAN ELI LILLY AND COMPANY (US) 1978-02-21 US disclosed
US-4001230-A ANTIBACTERIAL, ANTIPROTAZOAL ELI LILLY AND COMPANY (US) 1977-01-04 US disclosed
US-3980794-A Method for promoting growth of poultry with 3-(5-nitro-2-imidazolyl)pyrazoles ELI LILLY AND COMPANY (US) 1976-09-14 US disclosed
US-3947467-A ANTIBACTERIAL, ANTIPROTOZOAL, ANTIFUNGAL ELI LILLY AND COMPANY (US) 1976-03-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12465603-B2 Phthalazinone based modulators for the treatment of disease MKI67, BCL2, CCAR2 GAA 432/4885ALOX15 1253/4885MGAM 4213/4885
US-20260027113-A1 PHTHALAZINONE BASED MODULATORS FOR THE TREATMENT OF DISEASE NCOR1, NOP56, NCOR2 GAA 3714/4885ALOX15 2235/4885MGAM 4847/4885
US-20240374589-A1 PHTHALAZINONE BASED MODULATORS FOR THE TREATMENT OF DISEASE MKI67, HDAC6, BCL2 GAA 350/4885ALOX15 1407/4885MGAM 4156/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.