Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 1/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.32 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3598334 | 0.89 | KMT2A (0.31) | — | |
| SCHEMBL7000259 | 0.88 | MAPT (0.32) | — | |
| SCHEMBL7766420 | 0.81 | ALDH1A1 (0.35) | HSD17B10ALDH1A1 | |
| SCHEMBL8648027 | 0.80 | GRIN2D (0.35) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL812490 | 0.78 | — | — | |
| SCHEMBL8875145 | 0.75 | GRIN2D (0.32) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL7780291 | 0.74 | CRBN (0.33) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL8645554 | 0.72 | KMT2A (0.38) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL7781028 | 0.72 | HTR7 (0.32) | — | |
| SCHEMBL6839193 | 0.71 | ALDH1A1 (0.38) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0613885-B1 | Subsituted 1-H-3-phenyl-5-cycloalkyl-pyrrolidin-2,4-diones, their preparation and their use as parasiticides and herbicides | BAYER AG (DE) | 2001-09-19 | — | — | EP | disclosed |
| EP-0613884-B1 | Dialkyl-1-H-3(2,4-dimethylphenyl)-pyrrolidin-2,4-diones, their preparation and their use as parasiticides and herbicides | BAYER AG (DE) | 2001-06-20 | — | — | EP | disclosed |
| US-5602078-A | POSSESS HERBICIDAL AND PESTICIDAL ACTIVITY | BAYER AKTIENGESELLSCHAFT (DE) | 1997-02-11 | — | — | US | disclosed |
| US-5567671-A | HERBICIDES, PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-10-22 | — | — | US | disclosed |
| US-5504057-A | HERBICIDES; PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-04-02 | — | — | US | disclosed |
| EP-0613884-A2 | Dialkyl-1-H-3(2,4-dimethylphenyl)-pyrrolidin-2,4-diones, their preparation and their use as parasiticides and herbicides | BAYER AG (DE) | 1994-09-07 | — | — | EP | disclosed |