Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 7/20 | 0.62 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.60 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.60 |
| ▸ | MME | P08473 | 5/20 | 0.56 |
| ▸ | CPA1 | P15085 | 1/20 | 0.55 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 3/20 | 0.53 |
| ▸ | CA2 | P00918 | 3/20 | 0.53 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.50 |
| ▸ | ALB | P02768 | 1/20 | 0.49 |
| ▸ | IL2 | P60568 | 1/20 | 0.49 |
| ▸ | NHERF1 | O14745 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7769146 | 1.00 | ACE (0.62) | ACEFOLH1NAALAD2MMECPA1 | |
| SCHEMBL6306316 | 0.90 | ACE (0.62) | ACEFOLH1NAALAD2MMECPA1 | |
| SCHEMBL4161387 | 0.87 | ACE (0.62) | ACEFOLH1NAALAD2MMECPA1 | |
| SCHEMBL4161392 | 0.87 | ACE (0.62) | ACEFOLH1NAALAD2MMECPA1 | |
| SCHEMBL1991725 | 0.87 | ACE (0.62) | ACEFOLH1NAALAD2MMECPA1 | |
| SCHEMBL1991726 | 0.87 | ACE (0.62) | ACEFOLH1NAALAD2MMECPA1 | |
| SCHEMBL21777173 | 0.86 | MME (0.61) | ACENAALAD2MMECPA1ACE2 | |
| SCHEMBL6757142 | 0.85 | PTPN2 (0.52) | ACEFOLH1NAALAD2CA1SLC7A5 | |
| SCHEMBL3459805 | 0.85 | ACE (0.60) | ACEFOLH1NAALAD2MMECPA1 | |
| SCHEMBL16892795 | 0.85 | ACE (0.60) | ACEFOLH1NAALAD2MMECPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000077520-A1 | LABELLING OF PEPTIDES AND PROTEINS | PROTEOSYS AG (DE) | 2000-12-21 | — | — | WO | claimed |
| EP-1059531-A1 | Labelling of peptides and proteins | Nordheim, Alfred, Prof. Dr. (DE) | 2000-12-13 | — | — | EP | claimed |
| CN-115515928-B | Method for analyzing polysulfide, method for inhibiting hydrolysis of polysulfide, and use of N-iodoacetyl-L-tyrosine methyl ester | 公立大学法人大阪 | 2024-05-10 | — | — | CN | disclosed |
| US-20230147021-A1 | POLYSULFIDE STABILIZATION | UNIVERSITY PUBLIC CORPORATION OSAKA (JP) | 2023-05-11 | — | — | US | disclosed |
| CN-115515928-A | Stabilization of polysulfides | 公立大学法人大阪 | 2022-12-23 | — | — | CN | disclosed |
| WO-2001094945-A2 | METHOD FOR ENHANCING THE SOLUBILITY OF PROTEINS BY ALKYLATING REAGENTS | PROTEOSYS AG (DE) | 2001-12-13 | — | — | WO | disclosed |
| WO-2000077520-A1 | LABELLING OF PEPTIDES AND PROTEINS | PROTEOSYS AG (DE) | 2000-12-21 | — | — | WO | disclosed |
| EP-1059531-A1 | Labelling of peptides and proteins | Nordheim, Alfred, Prof. Dr. (DE) | 2000-12-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230147021-A1 | POLYSULFIDE STABILIZATION | YWHAZ, YWHAH, PTPN21 | ACE 3452/4885FOLH1 2950/4885NAALAD2 2538/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.