Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN2 | P17706 | 1/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.52 |
| ▸ | ACE | P12821 | 3/20 | 0.51 |
| ▸ | HPGDS | O60760 | 4/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | NPY1R | P25929 | 1/20 | 0.45 |
| ▸ | NPY2R | P49146 | 1/20 | 0.45 |
| ▸ | NPY4R | P50391 | 1/20 | 0.45 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.45 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.45 |
| ▸ | FCER2 | P06734 | 1/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.44 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | CHRND | Q07001 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4386989 | 0.87 | PTPN2 (0.52) | PTPN2PTPN1ACEHPGDSCA12 | |
| SCHEMBL5594950 | 0.87 | PTPN2 (0.52) | PTPN2PTPN1ACEHPGDSCA12 | |
| Hydrochloric Acid SCHEMBL12469709 | 0.86 | PTPN2 (0.51) | PTPN2PTPN1ACEHPGDSCA12 | |
| SCHEMBL13649440 | 0.85 | HPGDS (0.56) | PTPN1HPGDSFCER2 | |
| SCHEMBL7769146 | 0.85 | ACE (0.62) | ACECA1SLC7A5FOLH1NAALAD2 | |
| SCHEMBL7769148 | 0.85 | ACE (0.62) | ACECA1SLC7A5FOLH1NAALAD2 | |
| SCHEMBL14136194 | 0.84 | GRIA1 (0.54) | PTPN2PTPN1ACEHPGDSNPY1R | |
| SCHEMBL20729856 | 0.84 | PTPN2 (0.50) | PTPN2PTPN1ACEHPGDSNPY1R | |
| SCHEMBL26605060 | 0.84 | OPRD1 (0.48) | PTPN2PTPN1ACEHPGDSOPRD1 | |
| SCHEMBL26605068 | 0.84 | OPRD1 (0.48) | PTPN2PTPN1ACEHPGDSOPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6770740-B1 | PEPTIDE- DNA CARRIER COMPOSITIONS AND CONDENSED PARTICLES WITH REDUCED TOXICITY AND INCREASED STABILITY; USED IN COMBINATION WITH BIOCOMPATIBLE MATRICES, CARRIERS AND/OR TARGETING AGENTS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2004-08-03 | — | — | US | disclosed |
| WO-2001004135-A2 | CROSSLINKED DNA CONDENSATE COMPOSITIONS AND GENE DELIVERY METHODS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2001-01-18 | — | — | WO | disclosed |