SCHEMBL7769223

SCHEMBL7769223

[SiH3][Ti](Cl)(Cl)(C1C=Cc2ccccc21)C1C=Cc2ccccc21

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.35
HTR6 P50406 1/20 0.35
BRD4 O60885 1/20 0.33
CCL2 P13500 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2538857 0.80 HTR2A (0.35) HTR2AHTR6BRD4CCL2
SCHEMBL3381692 0.80 BRD4 (0.36) HTR2AHTR6BRD4CCL2
SCHEMBL3385102 0.77 HTR6 (0.33) HTR2AHTR6BRD4CCL2
SCHEMBL4457209 0.77 BRD4 (0.34) HTR2AHTR6BRD4CCL2
SCHEMBL6228139 0.76 BRD4 (0.33) HTR2AHTR6BRD4CCL2
SCHEMBL393668 0.76 HTR2A (0.36) HTR2AHTR6BRD4CCL2
SCHEMBL7937299 0.76 HTR2A (0.36) HTR2AHTR6BRD4CCL2
SCHEMBL714329 0.76 BRD4 (0.33) HTR2AHTR6BRD4CCL2
SCHEMBL721920 0.76 BRD4 (0.33) HTR2AHTR6BRD4CCL2
SCHEMBL2534841 0.76 BRD4 (0.33) HTR2AHTR6BRD4CCL2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001098374-A2 PROCESS OF PRODUCING SELF-SUPPORTED CATALYSTS ALBEMARLE CORPORATION (US) 2001-12-27 WO disclosed
WO-2001098381-A2 POLYMERIZATION PROCESS USING SELF-SUPPORTED CATALYSTS ALBEMARLE CORPORATION (US) 2001-12-27 WO disclosed