Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28935895 | 0.82 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2HPGDHTTLMNA | |
| SCHEMBL23209724 | 0.81 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2HPGDHTTLMNA | |
| SCHEMBL28061827 | 0.78 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2HPGDHTTLMNA | |
| SCHEMBL897268 | 0.77 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2HPGDHTTLMNA | |
| SCHEMBL2557672 | 0.77 | PPARG (0.54) | ALDH1A1SMN1; SMN2HPGDHTTLMNA | |
| SCHEMBL26090923 | 0.76 | ADRA2A (0.44) | ALDH1A1SMN1; SMN2HPGDHTTLMNA | |
| SCHEMBL10588375 | 0.76 | PTGDR2 (0.44) | ALDH1A1SMN1; SMN2HPGDHTTLMNA | |
| SCHEMBL11673199 | 0.75 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2HPGDHTTLMNA | |
| SCHEMBL11267013 | 0.74 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2HPGDHTTLMNA | |
| SCHEMBL7879918 | 0.74 | ADRA2A (0.45) | ALDH1A1SMN1; SMN2HPGDHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001074810-A2 | METHOD FOR USING 2-ARYLOXYALKYLAMINOBENZOXAZOLES AND 2-ARYLOXYALKYLAMINOBENZOTHIAZOLES AS H3 ANTAGONISTS | ORTHO MCNEIL PHARMACEUTICAL, INC. (US) | 2001-10-11 | — | — | WO | disclosed |