Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL897268 | 0.95 | ALDH1A1 (0.49) | ADRA2AADRA2BADRA2CALDH1A1HTT | |
| SCHEMBL26089915 | 0.88 | ADRA2A (0.42) | ADRA2AADRA2BADRA2CALDH1A1HTT | |
| SCHEMBL26089572 | 0.87 | ADRA2A (0.40) | ADRA2AADRA2BADRA2CALDH1A1HTT | |
| SCHEMBL26091404 | 0.86 | ADRA2A (0.39) | ADRA2AADRA2BADRA2CALDH1A1HTT | |
| SCHEMBL24590618 | 0.85 | ADRA2A (0.41) | ADRA2AADRA2BADRA2CALDH1A1HTT | |
| SCHEMBL16195622 | 0.85 | ADRA2A (0.42) | ADRA2AADRA2BADRA2CALDH1A1HTT | |
| SCHEMBL417898 | 0.82 | USP2 (0.44) | ADRA2AADRA2BADRA2CALDH1A1HTT | |
| SCHEMBL25757370 | 0.81 | CTRC (0.47) | ALDH1A1HTTHPGDSMN1; SMN2LMNA | |
| SCHEMBL1082121 | 0.81 | HTT (0.50) | ALDH1A1HTTSMN1; SMN2LMNAGAA | |
| SCHEMBL10805994 | 0.80 | USP2 (0.45) | ADRA2AADRA2BADRA2CALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288276-B1 | CARBONYLATION OF MAGNESIUM SALT OF PHENOL WITH FORMALDEHYDE THEN REACTION WITH AMINE TO FORM OXIME | HENKEL KOMMANDITGESELSCHAFT AUF AKTIEN (DE) | 2001-09-11 | — | — | US | disclosed |
| US-6274068-B1 | Synthesis of 2-hydroxyarylaldehydes | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2001-08-14 | — | — | US | disclosed |
| WO-2000040534-A1 | SALICYLALDOXIMES AND METHOD OF PREPARATION | COGNIS DEUTSCHLAND GMBH (DE) | 2000-07-13 | — | — | WO | disclosed |
| US-5856583-A | Synthesis of 2-hydroxyarylaldehydes | ALLCO CHEMICAL CORP. (US) | 1999-01-05 | — | — | US | disclosed |