Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7769259 | 0.76 | KMT2A (0.42) | KMT2APOLBPTPN1RAB9ASMN1; SMN2 | |
| SCHEMBL335773 | 0.72 | KCNN4 (0.37) | SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL13626299 | 0.71 | KMT2A (0.41) | KMT2ARAB9ASMN1; SMN2MEN1MAPT | |
| SCHEMBL9812553 | 0.68 | ALDH1A1 (0.38) | KMT2APOLBRAB9ASMN1; SMN2MEN1 | |
| SCHEMBL11464164 | 0.67 | KMT2A (0.44) | KMT2APOLBPKMPTPN1PTPN7 | |
| SCHEMBL11463200 | 0.67 | KMT2A (0.41) | KMT2APOLBPKMPTPN1PTPN7 | |
| SCHEMBL12674134 | 0.64 | KDM4E (0.40) | KMT2ARAB9ASMN1; SMN2MEN1MAPT | |
| SCHEMBL9812559 | 0.63 | MAPT (0.38) | KMT2APOLBPKML3MBTL1RAB9A | |
| SCHEMBL11033469 | 0.63 | MAPT (0.37) | KMT2APOLBPKMPTPN1PTPN7 | |
| SCHEMBL28968872 | 0.62 | MAPT (0.42) | KMT2APOLBPKMPTPN1PTPN7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8097758-B2 | Isoserine derivatives for use as coagulation factor IXa inhibitors | SANOFI-AVENTIS (FR) | 2012-01-17 | — | — | US | disclosed |