Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.46 |
| ▸ | RXRB | P28702 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TPMT | P51580 | 1/20 | 0.44 |
| ▸ | RARB | P10826 | 6/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.42 |
| ▸ | PLK1 | P53350 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | RARA | P10276 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1355567 | 0.95 | ALDH1A1 (0.45) | RXRARXRBALDH1A1NPC1TP53 | |
| SCHEMBL27912534 | 0.88 | POLB (0.45) | ALDH1A1NPC1TP53RAB9ASMN1; SMN2 | |
| SCHEMBL11811437 | 0.88 | CA12 (0.56) | ALDH1A1NPC1TP53RAB9ASMN1; SMN2 | |
| SCHEMBL9701286 | 0.87 | RARB (0.59) | ALDH1A1NPC1RAB9ARARBL3MBTL1 | |
| SCHEMBL28376268 | 0.86 | TPMT (0.42) | RXRARXRBALDH1A1NPC1TP53 | |
| SCHEMBL16186344 | 0.86 | TPMT (0.57) | RXRARXRBALDH1A1NPC1TP53 | |
| SCHEMBL27782228 | 0.85 | GPR84 (0.61) | ALDH1A1RARBPLA2G2AGPR84MEN1 | |
| SCHEMBL14118049 | 0.84 | RARB (0.62) | ALDH1A1RARBPLA2G2AGPR84MEN1 | |
| SCHEMBL27760653 | 0.84 | RARB (0.62) | ALDH1A1RARBPLA2G2AGPR84MEN1 | |
| SCHEMBL3547435 | 0.83 | PLA2G2A (0.46) | RXRAALDH1A1NPC1TP53RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2785752-B1 | INTERNAL ELECTRON DONOR FOR OLEFIN POLYMERIZATION CATALYSTS, METHOD OF MAKING AND USING THE SAME | BRASKEM AMERICA INC (US) | 2023-05-31 | — | — | EP | claimed |
| CN-101560272-B | Olefinic polymerization catalyst, preparation method and polymerization method | YINGKOU XIANGYANG CATALYST CO LTD | 2011-04-13 | — | — | CN | disclosed |
| CN-101560273-B | Olefinic polymerization catalyst, preparation method and polymerization method | YINGKOU XIANGYANG CATALYST CO LTD | 2011-03-23 | — | — | CN | disclosed |
| CN-101560272-A | Olefinic polymerization catalyst, preparation method and polymerization method | YINGKOU XIANGYANG CATALYST CO (CN) | 2009-10-21 | — | — | CN | disclosed |
| CN-101560273-A | Olefinic polymerization catalyst, preparation method and polymerization method | YINGKOU XIANGYANG CATALYST CO (CN) | 2009-10-21 | — | — | CN | disclosed |
| WO-2001070662-A2 | 2,4-PENTADIENOIC ACID DERIVATIVES HAVING SELECTIVE ACTIVITY FOR RETINOID X (RXR) RECEPTORS | ALLERGAN , INC. (US) | 2001-09-27 | — | — | WO | disclosed |
| EP-1117628-A1 | 2, 4-PENTADIENOIC ACID DERIVATIVES HAVING SELECTIVE ACTIVITY FOR RETINOID X (RXR) RECEPTORS | Allergan Sales, Inc. (US) | 2001-07-25 | — | — | EP | disclosed |
| WO-2000020370-A1 | 2, 4-PENTADIENOIC ACID DERIVATIVES HAVING SELECTIVE ACTIVITY FOR RETINOID X (RXR) RECEPTORS | ALLERGAN SALES, INC. (US) | 2000-04-13 | — | — | WO | disclosed |