Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 2/20 | 0.36 |
| ▸ | ACE | P12821 | 1/20 | 0.36 |
| ▸ | S100A4 | P26447 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | SDCBP | O00560 | 1/20 | 0.34 |
| ▸ | SDC2 | P34741 | 1/20 | 0.34 |
| ▸ | CTSD | P07339 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.32 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.32 |
| ▸ | METAP2 | P50579 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7766815 | 0.75 | CRBN (0.43) | CRBNS100A4IDO1CTSDMAPT | |
| SCHEMBL7769294 | 0.74 | CRBN (0.42) | CRBNACES100A4SDCBPSDC2 | |
| SCHEMBL7764873 | 0.71 | CYP2C19 (0.41) | CRBNSMN1; SMN2 | |
| SCHEMBL7766761 | 0.70 | CYP3A4 (0.40) | CRBNS100A4IDO1MAPTSMN1; SMN2 | |
| SCHEMBL7766827 | 0.69 | CYP2C19 (0.39) | CRBNSMN1; SMN2 | |
| SCHEMBL7765770 | 0.68 | CYP2C19 (0.38) | CRBNSMN1; SMN2 | |
| SCHEMBL28130589 | 0.66 | ACE (0.44) | ACES100A4PPARGPPARAMETAP2 | |
| SCHEMBL9217462 | 0.66 | ACE (0.44) | ACES100A4PPARGPPARAMETAP2 | |
| SCHEMBL7764999 | 0.66 | ALDH1A1 (0.37) | MAPTSMN1; SMN2 | |
| SCHEMBL7764980 | 0.66 | CYP3A4 (0.35) | IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0639566-B1 | CYCLIC COMPOUND | SANTEN PHARMACEUTICAL CO LTD (JP) | 2001-06-20 | — | — | EP | disclosed |
| US-5461158-A | Immunodeficiency and autoimmune diseases | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1995-10-24 | — | — | US | disclosed |
| EP-0639566-A1 | CYCLIC COMPOUND | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1995-02-22 | — | — | EP | disclosed |