Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 4/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.32 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7769372 | 0.84 | CAPN1 (0.42) | HTTCTSKCTSSCAPN1 | |
| SCHEMBL7769348 | 0.83 | TSHR (0.40) | HTTCTSKTSHRLMNACYP3A4 | |
| SCHEMBL7771083 | 0.80 | MGAM (0.38) | HTTCTSKLMNACTSSSMN1; SMN2 | |
| SCHEMBL7766024 | 0.79 | HTT (0.42) | HTTCTSKTSHRLMNACYP3A4 | |
| SCHEMBL7765999 | 0.77 | CTSK (0.33) | CTSKCTSSSMN1; SMN2 | |
| SCHEMBL7771079 | 0.77 | HTT (0.40) | HTTCTSKTSHRLMNACYP3A4 | |
| SCHEMBL7771335 | 0.77 | HTT (0.40) | HTTTSHRLMNACYP3A4NFKB1 | |
| SCHEMBL7769905 | 0.76 | CTSK (0.37) | CTSKCTSS | |
| SCHEMBL13777212 | 0.74 | TSHR (0.50) | HTTTSHRLMNACYP3A4NFKB1 | |
| SCHEMBL12150135 | 0.71 | HTT (0.41) | HTTTSHRLMNACYP3A4NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0765879-B1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO CO (JP) | 2001-02-14 | — | — | EP | disclosed |
| US-5861429-A | MITICIDES AND ANTHELMINTICS | SANKYO COMPANY, LIMITED (JP) | 1999-01-19 | — | — | US | disclosed |
| EP-0765879-A1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO COMPANY LIMITED (JP) | 1997-04-02 | — | — | EP | disclosed |