Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 8/20 | 0.40 |
| ▸ | CTSS | P25774 | 5/20 | 0.40 |
| ▸ | CTSL | P07711 | 5/20 | 0.40 |
| ▸ | CTSB | P07858 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NOS3 | P29474 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 1/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27904264 | 0.84 | CAPN1 (0.42) | CAPN1CTSKCTSSCTSLCTSB | |
| SCHEMBL3805990 | 0.84 | CNR2 (0.46) | CAPN1CTSKCTSSCTSLCTSB | |
| SCHEMBL7769375 | 0.84 | CNR2 (0.46) | CAPN1CTSKCTSSCTSLCTSB | |
| SCHEMBL7769345 | 0.84 | HTT (0.40) | CAPN1CTSKCTSSHTT | |
| SCHEMBL7766024 | 0.80 | HTT (0.42) | CAPN1CTSKCTSSCTSLCTSB | |
| SCHEMBL7769886 | 0.80 | CTSK (0.41) | CTSKCTSSCTSLCTSBHTT | |
| SCHEMBL7770027 | 0.79 | CTSK (0.40) | CTSKCTSSCTSLCTSBFOLH1 | |
| SCHEMBL7771100 | 0.78 | CTSL (0.43) | CTSKCTSSCTSLCTSBFOLH1 | |
| SCHEMBL7771079 | 0.78 | HTT (0.40) | CTSKCTSSCTSLCTSBHTT | |
| SCHEMBL3809516 | 0.77 | CTSL (0.43) | CAPN1CTSKCTSSCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0765879-B1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO CO (JP) | 2001-02-14 | — | — | EP | disclosed |
| US-5861429-A | MITICIDES AND ANTHELMINTICS | SANKYO COMPANY, LIMITED (JP) | 1999-01-19 | — | — | US | disclosed |
| EP-0765879-A1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO COMPANY LIMITED (JP) | 1997-04-02 | — | — | EP | disclosed |