Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.46 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | REN | P00797 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 4/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 1/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 2/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | HPGDS | O60760 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3805990 | 1.00 | CNR2 (0.46) | CNR2CAPN1CNR1TSHRLMNA | |
| SCHEMBL7769372 | 0.84 | CAPN1 (0.42) | CAPN1HTTCTSKNOS3NOS1 | |
| SCHEMBL27904264 | 0.84 | CAPN1 (0.42) | CAPN1HTTCTSKNOS3NOS1 | |
| SCHEMBL7769348 | 0.84 | TSHR (0.40) | CNR2CAPN1TSHRLMNACYP3A4 | |
| SCHEMBL7766030 | 0.80 | HTT (0.42) | CNR2CAPN1TSHRLMNACYP3A4 | |
| SCHEMBL7883345 | 0.80 | SMN1; SMN2 (0.45) | CNR2CTSKCTSLCTSBCTSS | |
| SCHEMBL7769892 | 0.80 | PPID (0.42) | CNR1CTSKHPGDSFOLH1 | |
| SCHEMBL3807501 | 0.80 | HTT (0.42) | CNR2CAPN1TSHRLMNACYP3A4 | |
| SCHEMBL7770030 | 0.79 | KCNA5 (0.40) | CNR2CTSKCTSLCTSBCTSS | |
| SCHEMBL13604066 | 0.78 | CAPN1 (0.39) | CNR2CAPN1TSHRLMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103124722-B | Method for producing amino acid amide derivative having fluorine-containing carbamate group, production intermediate thereof, and method for producing ethylene diamine derivative | MITSUI CHEMICALS AGRO INC | 2014-11-12 | — | — | CN | disclosed |
| CN-101405259-B | Process for production of ethylenediamine derivative having halogenated carbamate group and acyl group, and intermediated for production of the derivative | MITSU CHEMICALS INC | 2013-06-19 | — | — | CN | disclosed |
| CN-103124722-A | Method for producing amino acid amide derivative having fluorine-containing carbamate group, production intermediate thereof, and method for producing ethylene diamine derivative | MITSUI CHEMICALS AGRO INC | 2013-05-29 | — | — | CN | disclosed |
| CN-101405259-A | Process for production of ethylenediamine derivative having halogenated carbamate group and acyl group, and intermediated for production of the derivative | MITSUI CHEMICALS INC (JP) | 2009-04-08 | — | — | CN | disclosed |
| EP-0765879-B1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO CO (JP) | 2001-02-14 | — | — | EP | disclosed |
| US-5861429-A | MITICIDES AND ANTHELMINTICS | SANKYO COMPANY, LIMITED (JP) | 1999-01-19 | — | — | US | disclosed |
| EP-0765879-A1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO COMPANY LIMITED (JP) | 1997-04-02 | — | — | EP | disclosed |