Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 5/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 5/20 | 0.38 |
| ▸ | HPGDS | O60760 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 2/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
| ▸ | LAP3 | P28838 | 2/20 | 0.37 |
| ▸ | TYR | P14679 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22341332 | 0.84 | ALDH1A1 (0.56) | CTSKFOLH1ALDH1A1LAP3TYR | |
| SCHEMBL7769892 | 0.84 | PPID (0.42) | CTSKFOLH1HPGDSALDH1A1LAP3 | |
| SCHEMBL4073412 | 0.84 | ALDH1A1 (0.56) | CTSKFOLH1ALDH1A1LAP3TYR | |
| SCHEMBL7883345 | 0.84 | SMN1; SMN2 (0.45) | KCNA5CTSKFOLH1HPGDSALDH1A1 | |
| SCHEMBL7770027 | 0.83 | CTSK (0.40) | CTSKFOLH1ALDH1A1CTSSCTSL | |
| SCHEMBL7766007 | 0.82 | CAD (0.34) | CTSKCTSSCTSL | |
| SCHEMBL7771103 | 0.82 | ALDH1A1 (0.42) | CTSKFOLH1HPGDSALDH1A1CTSS | |
| SCHEMBL31463591 | 0.81 | PPID (0.46) | CTSKFOLH1TYR | |
| SCHEMBL12987679 | 0.81 | PPID (0.46) | CTSKFOLH1TYR | |
| SCHEMBL7278909 | 0.80 | RAB9A (0.42) | FOLH1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0765879-B1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO CO (JP) | 2001-02-14 | — | — | EP | disclosed |
| US-5861429-A | MITICIDES AND ANTHELMINTICS | SANKYO COMPANY, LIMITED (JP) | 1999-01-19 | — | — | US | disclosed |
| EP-0765879-A1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO COMPANY LIMITED (JP) | 1997-04-02 | — | — | EP | disclosed |