Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | ACHE | P22303 | 4/20 | 0.52 |
| ▸ | BCHE | P06276 | 3/20 | 0.52 |
| ▸ | MAOB | P27338 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7676833 | 0.87 | HSP90AA1 (0.61) | HRH3SMN1; SMN2ACHEBCHEMAOB | |
| SCHEMBL7680253 | 0.80 | ACHE (0.74) | ACHEBCHE | |
| SCHEMBL6549840 | 0.79 | HRH2 (0.54) | HRH3ACHEBCHEMAOBCYP2D6 | |
| SCHEMBL6549844 | 0.79 | HRH2 (0.54) | HRH3ACHEBCHEMAOBCYP2D6 | |
| SCHEMBL13227205 | 0.78 | HSP90AA1 (0.74) | HRH3SMN1; SMN2ACHEBCHEMAOB | |
| SCHEMBL6058964 | 0.77 | APP (0.66) | SMN1; SMN2MAOBLMNAPOLB | |
| SCHEMBL22882051 | 0.77 | POLB (0.56) | SMN1; SMN2MAOBLMNAPOLBEGFR | |
| SCHEMBL6058957 | 0.77 | APP (0.66) | SMN1; SMN2MAOBLMNAPOLB | |
| SCHEMBL4090529 | 0.77 | HRH3 (0.67) | HRH3ACHEBCHEMAOB | |
| SCHEMBL4090531 | 0.77 | HRH3 (0.67) | HRH3ACHEBCHEMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1115697-A1 | UNSATURATED HYDROXIMIC ACID DERIVATIVES AS PARP INHIBITORS | N-Gene Kutato KFT. (HU) | 2001-07-18 | — | — | EP | disclosed |
| WO-2000014054-A1 | UNSATURATED HYDROXIMIC ACID DERIVATIVES AS PARP INHIBITORS | N-Gene Kutató Kft. (HU) | 2000-03-16 | — | — | WO | disclosed |