Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.61 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.56 |
| ▸ | AKR1B10 | O60218 | 3/20 | 0.55 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 4/20 | 0.53 |
| ▸ | BCHE | P06276 | 3/20 | 0.53 |
| ▸ | MAOB | P27338 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7769407 | 0.87 | HRH3 (0.57) | HSP90AA1HRH3SMN1; SMN2ACHEBCHE | |
| SCHEMBL6549840 | 0.86 | HRH2 (0.54) | HSP90AA1HRH3KDM4EACHEBCHE | |
| SCHEMBL6549844 | 0.86 | HRH2 (0.54) | HSP90AA1HRH3KDM4EACHEBCHE | |
| SCHEMBL15347088 | 0.81 | AKR1B10 (0.73) | AKR1B10AKR1B1MEN1KMT2AALDH1A1 | |
| SCHEMBL13834132 | 0.81 | AKR1B10 (0.73) | AKR1B10AKR1B1MEN1KMT2AALDH1A1 | |
| SCHEMBL12083424 | 0.81 | AKR1B10 (0.73) | AKR1B10AKR1B1MEN1KMT2AALDH1A1 | |
| SCHEMBL7680253 | 0.80 | ACHE (0.74) | KMT2AKDM4EALDH1A1ACHEBCHE | |
| SCHEMBL13833758 | 0.80 | AKR1B10 (0.71) | AKR1B10AKR1B1MEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL11550499 | 0.79 | MEN1 (0.57) | HSP90AA1AKR1B10AKR1B1MEN1KMT2A | |
| SCHEMBL21203260 | 0.78 | MAOB (0.60) | HRH3MEN1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6500823-B1 | ENERGY DEFICIENCY OF THE CELL CAUSED BY PARP INHIBITION, IN DIABETES COMPLICATIONS, IN OXYGEN DEFICIENT STATUS OF THE HEART AND BRAIN, IN NEURODEGENERATIVE DISEASES, IN THE TREATMENT OF AUTOIMMUNE AND/OR VIRAL DISEASES | N-GENE RESEARCH LABORATORIES, INC. | 2002-12-31 | — | — | US | claimed |