Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.43 |
| ▸ | GAA | P10253 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9326030 | 0.80 | L3MBTL1 (0.52) | L3MBTL1ALDH1A1GAAMAPTHPGD | |
| SCHEMBL3655006 | 0.78 | ALDH1A1 (0.35) | L3MBTL1ALDH1A1GAAHPGD | |
| SCHEMBL306065 | 0.78 | CTSA (0.45) | L3MBTL1ALDH1A1GAAMAPTHPGD | |
| SCHEMBL21801447 | 0.76 | L3MBTL1 (0.48) | L3MBTL1ALDH1A1GAAMAPTHPGD | |
| SCHEMBL7767858 | 0.76 | PTK2 (0.40) | L3MBTL1MAPTKMT2AMEN1 | |
| SCHEMBL27756885 | 0.76 | F2 (0.45) | L3MBTL1ALDH1A1GAAMAPTHPGD | |
| SCHEMBL1732930 | 0.74 | L3MBTL1 (0.45) | L3MBTL1ALDH1A1GAAMAPTHPGD | |
| SCHEMBL12806428 | 0.74 | L3MBTL1 (0.47) | L3MBTL1ALDH1A1GAAMAPTHPGD | |
| SCHEMBL11586322 | 0.74 | FAAH (0.56) | ALDH1A1 | |
| SCHEMBL9326634 | 0.73 | JAK2 (0.46) | L3MBTL1ALDH1A1MAPTHPGDF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0778264-B1 | Tertiary amines having antimycotic and cholesterol lowering activity | HOFFMANN LA ROCHE (CH) | 2001-07-11 | — | — | EP | disclosed |
| EP-0778264-A1 | Tertiary amines having antimycotic and cholesterol lowering activity | F. HOFFMANN-LA ROCHE AG (CH) | 1997-06-11 | — | — | EP | disclosed |