Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP2 | P42575 | 1/20 | 0.57 |
| ▸ | CTSD | P07339 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NAAA | Q02083 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | FAAH | O00519 | 3/20 | 0.42 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7771126 | 0.89 | CASP2 (0.67) | CASP2CTSDHDAC3HDAC1HDAC2 | |
| SCHEMBL1418983 | 0.87 | CASP2 (0.53) | CASP2NAAAFAAHDNM1 | |
| SCHEMBL13819835 | 0.85 | CASP2 (0.74) | CASP2NAAAFAAHDNM1MEN1 | |
| SCHEMBL5983516 | 0.85 | FAAH (0.61) | CASP2NAAAFAAHDNM1MEN1 | |
| SCHEMBL7828830 | 0.84 | MEN1 (0.58) | CASP2CTSDNAAAALDH1A1FAAH | |
| SCHEMBL241545 | 0.84 | FAAH (0.65) | CASP2NAAAFAAHDNM1MEN1 | |
| SCHEMBL241202 | 0.84 | FAAH (0.65) | CASP2NAAAFAAHDNM1MEN1 | |
| SCHEMBL14812783 | 0.84 | FAAH (0.65) | CASP2NAAAFAAHDNM1MEN1 | |
| SCHEMBL240541 | 0.84 | FAAH (0.65) | CASP2NAAAFAAHDNM1MEN1 | |
| SCHEMBL5050329 | 0.84 | FAAH (0.65) | CASP2NAAAFAAHDNM1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023168367-A1 | QUINOLINE cGAS ANTAGONIST COMPOUNDS | IMMUNESENSOR THERAPEUTICS, INC. (US) | 2023-09-07 | — | — | WO | disclosed |
| EP-0765879-B1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO CO (JP) | 2001-02-14 | — | — | EP | disclosed |
| US-5861429-A | MITICIDES AND ANTHELMINTICS | SANKYO COMPANY, LIMITED (JP) | 1999-01-19 | — | — | US | disclosed |
| EP-0765879-A1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO COMPANY LIMITED (JP) | 1997-04-02 | — | — | EP | disclosed |