SCHEMBL7771126

SCHEMBL7771126

CCCC(=O)NCCCC(N)=O

nearest known ligand 0.67

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CASP2 P42575 1/20 0.67
NAAA Q02083 1/20 0.52
FAAH O00519 3/20 0.48
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48
CTSD P07339 1/20 0.48
DNM1 Q05193 1/20 0.46
HDAC3 O15379 1/20 0.44
HDAC1 Q13547 1/20 0.44
HDAC2 Q92769 1/20 0.44
HDAC8 Q9BY41 1/20 0.44
HDAC6 Q9UBN7 1/20 0.44
TSHR P16473 1/20 0.44
SLC6A5 Q9Y345 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13819835 0.92 CASP2 (0.74) CASP2NAAAFAAHMEN1KMT2A
SCHEMBL7769416 0.89 CASP2 (0.57) CASP2NAAAFAAHMEN1KMT2A
SCHEMBL7537764 0.86 CASP2 (0.86) CASP2NAAAFAAHMEN1KMT2A
SCHEMBL14576993 0.86 CASP2 (0.78) CASP2NAAAFAAHMEN1KMT2A
SCHEMBL11213979 0.86 CASP2 (0.60) CASP2NAAAFAAHMEN1KMT2A
SCHEMBL21587881 0.86 FAAH (0.68) CASP2NAAAFAAHMEN1KMT2A
SCHEMBL6684491 0.85 FAAH (0.61) CASP2NAAAFAAHDNM1SLC6A5
SCHEMBL1298169 0.85 CASP2 (0.59) CASP2NAAAFAAHMEN1KMT2A
SCHEMBL6686395 0.85 CASP2 (0.59) CASP2NAAAFAAHMEN1KMT2A
SCHEMBL10477936 0.84 MEN1 (0.70) CASP2NAAAFAAHMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3371150-B1 PROCESS FOR PREPARING BRIVARACETAM UCB Biopharma SRL (BE) 2021-08-18 EP disclosed
WO-2017076737-A1 CONTINUOUS PROCESS FOR PREPARING BRIVARACETAM UCB BIOPHARMA SPRL (BE) 2017-05-11 WO disclosed
WO-2017076738-A1 PROCESS FOR PREPARING BRIVARACETAM UCB BIOPHARMA SPRL (BE) 2017-05-11 WO disclosed
EP-0765879-B1 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests SANKYO CO (JP) 2001-02-14 EP disclosed
US-5861429-A MITICIDES AND ANTHELMINTICS SANKYO COMPANY, LIMITED (JP) 1999-01-19 US disclosed
EP-0765879-A1 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests SANKYO COMPANY LIMITED (JP) 1997-04-02 EP disclosed
US-5453363-A Solubilizing, reducing, and denaturing refractile bodies; oxidation with glutathione; genetic engineering BOEHRINGER MANNHEIM GMBH (DE) 1995-09-26 US disclosed