Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 1/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7773649 | 0.90 | HDAC1 (0.62) | HDAC2HDAC8HDAC6HDAC1HPGD | |
| SCHEMBL7773734 | 0.88 | HDAC1 (0.61) | HDAC2HDAC8HDAC6HDAC1MAPT | |
| SCHEMBL7450998 | 0.85 | HDAC2 (0.63) | HDAC2HDAC8HDAC6HDAC1MAPT | |
| Hydrocinnamoylglycine SCHEMBL29387246 | 0.85 | HDAC2 (0.63) | HDAC2HDAC8HDAC6HDAC1MAPT | |
| Hydrocinnamoylglycine SCHEMBL3995983 | 0.85 | HDAC2 (0.63) | HDAC2HDAC8HDAC6HDAC1MAPT | |
| Hydrochloric Acid SCHEMBL3658850 | 0.85 | HDAC2 (0.54) | HDAC2HDAC8HDAC6HDAC1MAPT | |
| Hydrochloric Acid SCHEMBL1627384 | 0.85 | HDAC2 (0.54) | HDAC2HDAC8HDAC6HDAC1MAPT | |
| SCHEMBL14468015 | 0.84 | HDAC2 (0.56) | HDAC2HDAC8MAPTHPGDALDH1A1 | |
| SCHEMBL7455811 | 0.83 | HDAC2 (0.66) | HDAC2HDAC8HDAC6HDAC1MAPT | |
| SCHEMBL16588648 | 0.82 | ALDH1A1 (0.63) | HDAC2HDAC8HDAC6HDAC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200276332-A1 | COMPOSITIONS AND METHODS FOR TREATING PAIN DISORDERS | MANSELL JOHN (US) | 2020-09-03 | — | — | US | disclosed |
| EP-0765879-B1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO CO (JP) | 2001-02-14 | — | — | EP | disclosed |
| US-5861429-A | MITICIDES AND ANTHELMINTICS | SANKYO COMPANY, LIMITED (JP) | 1999-01-19 | — | — | US | disclosed |
| EP-0765879-A1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO COMPANY LIMITED (JP) | 1997-04-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200276332-A1 | COMPOSITIONS AND METHODS FOR TREATING PAIN DISORDERS | CALCA, CALCB, CALCRL | HDAC2 4120/4885HDAC8 3812/4885HDAC6 2847/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.