SCHEMBL7769637

SCHEMBL7769637

[NH]C(=O)CCNC(=O)OCCCCCl

nearest known ligand 0.47

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ACHE P22303 14/20 0.47
EPHX2 P34913 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7769638 0.83 ACHE (0.47) ACHEEPHX2
SCHEMBL7773715 0.82 ACHE (0.42) ACHEEPHX2
SCHEMBL7771514 0.81 ACHE (0.62) ACHEEPHX2
SCHEMBL7773651 0.81 ACHE (0.44) ACHEEPHX2
SCHEMBL7769356 0.80 ACHE (0.35) ACHE
SCHEMBL11740011 0.77 ACHE (0.57) ACHEEPHX2
SCHEMBL7769332 0.77 ACHE (0.55) ACHEEPHX2
SCHEMBL16013673 0.76 ACHE (0.60) ACHEEPHX2
SCHEMBL29250462 0.74 ACHE (0.73) ACHEEPHX2
SCHEMBL5747611 0.73 ACHE (0.48) ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0765879-B1 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests SANKYO CO (JP) 2001-02-14 EP disclosed
US-5861429-A MITICIDES AND ANTHELMINTICS SANKYO COMPANY, LIMITED (JP) 1999-01-19 US disclosed
EP-0765879-A1 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests SANKYO COMPANY LIMITED (JP) 1997-04-02 EP disclosed