Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | KDM1A | O60341 | 4/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SCN1A | P35498 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.40 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7772370 | 0.91 | KDM1A (0.48) | ATMKDM1ASIGMAR1POLBALDH1A1 | |
| SCHEMBL7767898 | 0.82 | HRH3 (0.41) | SIGMAR1ACHEHRH3KMT2ACYP1A2 | |
| SCHEMBL7068328 | 0.77 | ALDH1A1 (0.46) | ATMKDM1ASIGMAR1POLBALDH1A1 | |
| SCHEMBL13456606 | 0.74 | POLB (0.44) | KDM1ASIGMAR1POLBACHEALDH1A1 | |
| SCHEMBL235080 | 0.71 | KDM4E (0.65) | SIGMAR1POLBALDH1A1HRH3KEAP1 | |
| SCHEMBL13428655 | 0.70 | ACHE (0.44) | SIGMAR1ACHEALDH1A1KMT2AKCNH2 | |
| SCHEMBL16417106 | 0.68 | ALDH1A1 (0.47) | ATMALDH1A1KMT2AKCNH2MAPT | |
| SCHEMBL11856358 | 0.68 | KDM4E (0.70) | SIGMAR1POLBACHEALDH1A1KEAP1 | |
| SCHEMBL10913328 | 0.68 | KDM4E (0.70) | SIGMAR1POLBALDH1A1KEAP1SMN1; SMN2 | |
| SCHEMBL3065336 | 0.68 | KEAP1 (0.52) | KDM1ASIGMAR1POLBALDH1A1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0700916-B1 | CEPHEM COMPOUND, PROCESS FOR PRODUCING THE SAME, AND ANTIBACTERIAL CONTAINING THE COMPOUND | OTSUKA KAGAKU KK (JP) | 2001-06-20 | — | — | EP | disclosed |
| US-5698544-A | ANTIBOIOTIC AGAINST METHICILLIN RESISTANCE STAPHYLOCOCCUS AUREUS | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1997-12-16 | — | — | US | disclosed |
| EP-0700916-A1 | CEPHEM COMPOUND, PROCESS FOR PRODUCING THE SAME, AND ANTIBACTERIAL CONTAINING THE COMPOUND | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1996-03-13 | — | — | EP | disclosed |