Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CASP2 | P42575 | 1/20 | 0.30 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.30 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7770620 | 0.80 | TSHR (0.38) | ALDH1A1FAAHSMN1; SMN2CASP2ITGB3 | |
| SCHEMBL13368240 | 0.78 | ECE1 (0.37) | ECE1ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2200631 | 0.78 | CA2 (0.38) | ECE1ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7765731 | 0.78 | ALDH1A1 (0.54) | ECE1ALDH1A1FAAHMEN1KMT2A | |
| SCHEMBL25436116 | 0.77 | — | — | |
| SCHEMBL2784004 | 0.76 | HDAC6 (0.40) | ECE1ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7828830 | 0.76 | MEN1 (0.58) | ECE1ALDH1A1FAAHMEN1KMT2A | |
| SCHEMBL12573540 | 0.76 | TSHR (0.42) | ECE1ALDH1A1CASP2ITGB3ITGA2B | |
| SCHEMBL7769353 | 0.76 | HDAC3 (0.39) | ECE1ALDH1A1FAAHMEN1KMT2A | |
| SCHEMBL7765966 | 0.76 | ALDH1A1 (0.46) | ECE1ALDH1A1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0765879-B1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO CO (JP) | 2001-02-14 | — | — | EP | disclosed |
| US-5861429-A | MITICIDES AND ANTHELMINTICS | SANKYO COMPANY, LIMITED (JP) | 1999-01-19 | — | — | US | disclosed |
| EP-0765879-A1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO COMPANY LIMITED (JP) | 1997-04-02 | — | — | EP | disclosed |