Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | ECE1 | P42892 | 2/20 | 0.37 |
| ▸ | FAAH | O00519 | 2/20 | 0.36 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.36 |
| ▸ | YAP1 | P46937 | 1/20 | 0.36 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.36 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.31 |
| ▸ | CASP2 | P42575 | 1/20 | 0.31 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.31 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28837343 | 0.88 | ALDH1A1 (0.65) | ALDH1A1SMN1; SMN2FAAHTEAD1YAP1 | |
| SCHEMBL7765847 | 0.82 | FAAH (0.52) | ALDH1A1SMN1; SMN2FAAHTSHRCASP2 | |
| SCHEMBL2200631 | 0.80 | CA2 (0.38) | ALDH1A1SMN1; SMN2ECE1TSHRKMT2A | |
| SCHEMBL13368240 | 0.80 | ECE1 (0.37) | ALDH1A1SMN1; SMN2ECE1TSHRKMT2A | |
| SCHEMBL7828830 | 0.78 | MEN1 (0.58) | ALDH1A1ECE1FAAHTSHRKMT2A | |
| SCHEMBL2784004 | 0.78 | HDAC6 (0.40) | ALDH1A1SMN1; SMN2ECE1KMT2AMEN1 | |
| SCHEMBL7769353 | 0.78 | HDAC3 (0.39) | ALDH1A1SMN1; SMN2ECE1FAAHKMT2A | |
| SCHEMBL7765966 | 0.78 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2ECE1KMT2AMEN1 | |
| SCHEMBL7769667 | 0.78 | ECE1 (0.35) | ALDH1A1SMN1; SMN2ECE1FAAHKMT2A | |
| SCHEMBL12573540 | 0.78 | TSHR (0.42) | ALDH1A1ECE1TSHRCASP2ITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0765879-B1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO CO (JP) | 2001-02-14 | — | — | EP | disclosed |
| US-5861429-A | MITICIDES AND ANTHELMINTICS | SANKYO COMPANY, LIMITED (JP) | 1999-01-19 | — | — | US | disclosed |
| EP-0765879-A1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO COMPANY LIMITED (JP) | 1997-04-02 | — | — | EP | disclosed |