Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.36 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 6/20 | 0.34 |
| ▸ | GAA | P10253 | 5/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | ESRRG | P62508 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ESRRB | O95718 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2780858 | 0.94 | ALDH1A1 (0.38) | CNR2CNR1ALDH1A1TSHRMAPT | |
| SCHEMBL7766414 | 0.85 | ESRRG (0.45) | CNR2ALDH1A1TSHRAOC3NOX1 | |
| SCHEMBL2778041 | 0.81 | CA1 (0.40) | ALDH1A1MAPTKDM4EHPGDPOLB | |
| SCHEMBL7769844 | 0.75 | MAPT (0.34) | CNR1ALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL27611924 | 0.75 | KDM4E (0.39) | ALDH1A1MAPTKDM4EHPGDMEN1 | |
| SCHEMBL27630941 | 0.75 | TPSAB1 (0.44) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL2781111 | 0.75 | PPIB (0.40) | ALDH1A1TSHRMAPTGAAKDM4E | |
| SCHEMBL27611950 | 0.73 | MEN1 (0.42) | ALDH1A1TSHRMAPTGAAKDM4E | |
| SCHEMBL27611926 | 0.70 | TSHR (0.43) | ALDH1A1TSHRGAANPC1SMN1; SMN2 | |
| SCHEMBL7720045 | 0.70 | ALDH1A1 (0.59) | CNR2CNR1ALDH1A1TSHRAOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0773956-B1 | PURIFIED FORM OF STREPTOGRAMINES, PREPARATION OF SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | AVENTIS PHARMA SA (FR) | 2001-07-04 | — | — | EP | disclosed |
| EP-0773956-A1 | PURIFIED FORM OF STREPTOGRAMINES, PREPARATION OF SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | Aventis Pharma S.A. (FR) | 1997-05-21 | — | — | EP | disclosed |
| WO-1996004298-A1 | PURIFIED FORM OF STREPTOGRAMINES, PREPARATION OF SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | RHONE-POULENC RORER S.A. (FR) | 1996-02-15 | — | — | WO | disclosed |