Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.31 |
| ▸ | LOX | P28300 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7765910 | 0.98 | ALDH1A1 (0.36) | ALDH1A1LMNATP53NLRP3 | |
| SCHEMBL5842919 | 0.98 | ALDH1A1 (0.36) | ALDH1A1LMNATP53NLRP3 | |
| SCHEMBL5842389 | 0.93 | ALDH1A1 (0.34) | ALDH1A1LMNATP53NLRP3 | |
| SCHEMBL5840322 | 0.82 | — | — | |
| SCHEMBL17653549 | 0.78 | LMNA (0.55) | ALDH1A1LMNA | |
| SCHEMBL6887416 | 0.78 | KMT2A (0.39) | ALDH1A1LMNATP53NLRP3LOX | |
| SCHEMBL9340855 | 0.76 | TSHR (0.57) | ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL3354872 | 0.76 | TP53 (0.38) | ALDH1A1LMNATP53NLRP3LOX | |
| SCHEMBL2810385 | 0.76 | SOAT1 (0.42) | ALDH1A1LMNATP53LOX | |
| SCHEMBL2567545 | 0.76 | TSHR (0.57) | ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0765879-B1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO CO (JP) | 2001-02-14 | — | — | EP | disclosed |
| US-5861429-A | MITICIDES AND ANTHELMINTICS | SANKYO COMPANY, LIMITED (JP) | 1999-01-19 | — | — | US | disclosed |
| EP-0765879-A1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO COMPANY LIMITED (JP) | 1997-04-02 | — | — | EP | disclosed |