Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 8/20 | 0.36 |
| ▸ | PNMT | P11086 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL79213 | 0.79 | IGF1R (0.58) | IGF1RALOX15SIGMAR1PNMTTAAR1 | |
| SCHEMBL29220740 | 0.78 | IDO1 (0.38) | IGF1RALOX15SIGMAR1PNMTTAAR1 | |
| SCHEMBL81436 | 0.74 | SKP2 (0.46) | IGF1RALOX15SIGMAR1PNMTTAAR1 | |
| SCHEMBL79509 | 0.74 | DAO (0.43) | IGF1RALOX15SIGMAR1PNMTTAAR1 | |
| SCHEMBL11707484 | 0.74 | GPR84 (0.55) | IGF1RALOX15GPR84IDO1 | |
| SCHEMBL16258888 | 0.73 | TRPA1 (0.39) | ALOX15SIGMAR1PNMTIDO1 | |
| SCHEMBL8211623 | 0.72 | IGF1R (0.59) | IGF1RALOX15SIGMAR1PNMTTAAR1 | |
| SCHEMBL7009306 | 0.72 | IGF1R (0.59) | IGF1RALOX15SIGMAR1PNMTTAAR1 | |
| SCHEMBL11389115 | 0.72 | IGF1R (0.59) | IGF1RALOX15SIGMAR1PNMTTAAR1 | |
| SCHEMBL19001409 | 0.71 | SKP2 (0.47) | IGF1RALOX15SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0727428-B1 | Novel silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the compositions | SHINETSU CHEMICAL CO (JP) | 2001-06-06 | — | — | EP | disclosed |
| US-5665271-A | Silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the compositions | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1997-09-09 | — | — | US | disclosed |
| EP-0727428-A1 | Novel silacyclohexane compounds, preparation thereof, liquid crystal compositions comprising the same, and liquid crystal devices comprising the compositions | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-08-21 | — | — | EP | disclosed |