Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | PNMT | P11086 | 1/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 13/20 | 0.49 |
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | PYGL | P06737 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8211623 | 1.00 | IGF1R (0.59) | IGF1RALOX15PNMTTAAR1SIGMAR1 | |
| SCHEMBL7009306 | 1.00 | IGF1R (0.59) | IGF1RALOX15PNMTTAAR1SIGMAR1 | |
| SCHEMBL79213 | 0.92 | IGF1R (0.58) | IGF1RALOX15PNMTTAAR1SIGMAR1 | |
| SCHEMBL177296 | 0.83 | PNMT (0.61) | IGF1RALOX15PNMTTAAR1SIGMAR1 | |
| SCHEMBL30019331 | 0.83 | PNMT (0.61) | IGF1RALOX15PNMTTAAR1SIGMAR1 | |
| SCHEMBL11331998 | 0.80 | PNMT (0.70) | IGF1RALOX15PNMTTAAR1SIGMAR1 | |
| SCHEMBL11066232 | 0.80 | SIGMAR1 (0.61) | IGF1RALOX15PNMTTAAR1SIGMAR1 | |
| SCHEMBL8905774 | 0.80 | IGF1R (0.59) | IGF1RALOX15PNMTTAAR1SIGMAR1 | |
| SCHEMBL22333700 | 0.80 | SIGMAR1 (0.61) | IGF1RALOX15PNMTTAAR1SIGMAR1 | |
| SCHEMBL11332031 | 0.80 | PNMT (0.70) | IGF1RALOX15PNMTTAAR1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4275201-A | Aryl substituted diketones | STERLING DRUG INC. (US) | 1981-06-23 | — | — | US | disclosed |
| US-4189500-A | VIRICIDES | STERLING DRUG INC. (US) | 1980-02-19 | — | — | US | disclosed |
| US-4171378-A | INSECTICIDES, VIRICIDES | STERLING DRUG INC. (US) | 1979-10-16 | — | — | US | disclosed |
| US-4125541-A | Aryl substituted ketones | STERLING DRUG INC. (US) | 1978-11-14 | — | — | US | disclosed |
| US-4125714-A | Aryl substituted cycloalkanones | STERLING DRUG INC. (US) | 1978-11-14 | — | — | US | disclosed |