SCHEMBL7770001

SCHEMBL7770001

CCNc1ccccc1-c1ccc(C#N)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
STAT3 P40763 1/20 0.48
HSD11B1 P28845 1/20 0.42
CYP11B2 P19099 3/20 0.42
CHRM3 P20309 1/20 0.41
CYP2A6 P11509 1/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
EGLN2 Q96KS0 1/20 0.39
ADORA2A P29274 2/20 0.39
ADORA1 P30542 2/20 0.39
MEN1 O00255 2/20 0.38
MAPT P10636 2/20 0.38
KMT2A Q03164 2/20 0.38
NPC1 O15118 1/20 0.38
POLB P06746 1/20 0.38
RAB9A P51151 1/20 0.38
TSHR P16473 2/20 0.38
HSD17B10 Q99714 1/20 0.38
ADORA2B P29275 1/20 0.38
LOXL2 Q9Y4K0 1/20 0.38
SLC22A12 Q96S37 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5904052 0.80 SMN1; SMN2 (0.56) SMN1; SMN2MEN1MAPTKMT2ANPC1
SCHEMBL8977550 0.80 MERTK (0.45) STAT3CHRM3SMN1; SMN2MEN1MAPT
SCHEMBL9306024 0.79 LMNA (0.46) SMN1; SMN2MEN1MAPTKMT2ANPC1
SCHEMBL19240226 0.78 SLC22A12 (0.63) HSD11B1CYP11B2EGLN2SLC22A12KDM4E
SCHEMBL9196333 0.77 SLC6A4 (0.44) CHRM3SMN1; SMN2MEN1MAPTKMT2A
SCHEMBL3904434 0.77 QPCT (0.49) STAT3CHRM3SMN1; SMN2MEN1MAPT
SCHEMBL18415207 0.77 SMN1; SMN2 (0.46) SMN1; SMN2MEN1MAPTKMT2ANPC1
SCHEMBL7174382 0.77 SMN1; SMN2 (0.42) SMN1; SMN2MEN1MAPTKMT2ANPC1
SCHEMBL21336895 0.77 STAT3 (0.48) STAT3CYP11B2CHRM3MEN1MAPT
SCHEMBL11671860 0.76 ALDH1A1 (0.44) CYP11B2CYP2A6EGLN2NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0705289-B1 CROSS-LINKABLE POLYMER, PARTICULARLY FOR OPTICAL AND NON-LINEAR OPTICAL USE, MATERIALS OR DEVICES USING SAME, AND METHOD FOR PREPARING SAID POLYMER FLAMEL TECHNOLOGIES SA (FR) 2001-08-08 EP disclosed
US-6001958-A POLYMER HAS ON AT LEAST TWO OF ITS ENDS, AT LEAST ONE REACTIVE END GROUP OF A DIFFERENT CHEMICAL TYPE FROM THAT OF THE GROUP PREDOMINANTLY USED IN POLYMERIZATION AND THE PREPARATION OF A POLYMER SKELETON. FLAMEL TECHNOLOGIES (FR) 1999-12-14 US disclosed
EP-0705289-A1 CROSS-LINKABLE POLYMER, PARTICULARLY FOR OPTICAL AND NON-LINEAR OPTICAL USE, MATERIALS OR DEVICES USING SAME, AND METHOD FOR PREPARING SAID POLYMER FLAMEL TECHNOLOGIES, Société Anonyme (FR) 1996-04-10 EP disclosed
WO-1995000571-A1 CROSS-LINKABLE POLYMER, PARTICULARLY FOR OPTICAL AND NON-LINEAR OPTICAL USE, MATERIALS OR DEVICES USING SAME, AND METHOD FOR PREPARING SAID POLYMER FLAMEL TECHNOLOGIES (FR) 1995-01-05 WO disclosed