Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 8/20 | 0.32 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7773702 | 0.89 | ACHE (0.38) | HTTACHE | |
| SCHEMBL7769630 | 0.88 | ALDH1A1 (0.37) | HTTACHE | |
| SCHEMBL7770044 | 0.81 | HTT (0.39) | HTTACHE | |
| SCHEMBL29362788 | 0.81 | HTT (0.42) | HTTACHE | |
| SCHEMBL7769991 | 0.81 | HTT (0.42) | HTT | |
| SCHEMBL25447803 | 0.79 | MEN1 (0.48) | HTTACHE | |
| SCHEMBL14001450 | 0.77 | HTT (0.42) | HTTACHE | |
| SCHEMBL12223162 | 0.77 | ACHE (0.47) | HTTACHE | |
| SCHEMBL7773705 | 0.76 | ACHE (0.39) | HTTACHE | |
| SCHEMBL24687424 | 0.76 | HTT (0.48) | HTTACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0765879-B1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO CO (JP) | 2001-02-14 | — | — | EP | disclosed |
| US-5861429-A | MITICIDES AND ANTHELMINTICS | SANKYO COMPANY, LIMITED (JP) | 1999-01-19 | — | — | US | disclosed |
| EP-0765879-A1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO COMPANY LIMITED (JP) | 1997-04-02 | — | — | EP | disclosed |