Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 12/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PRKACA | P17612 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7769633 | 0.95 | MAOA (0.40) | ACHEHTTMAOAMAOBALDH1A1 | |
| SCHEMBL7770044 | 0.91 | HTT (0.39) | ACHEHTTMAOAMAOB | |
| SCHEMBL25447803 | 0.85 | MEN1 (0.48) | ACHEHTTALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL7773702 | 0.84 | ACHE (0.38) | ACHEHTTALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL12097015 | 0.80 | ACHE (0.63) | ACHE | |
| SCHEMBL7769996 | 0.79 | HTT (0.42) | HTTMAOAMAOBALDH1A1SMN1; SMN2 | |
| SCHEMBL14001450 | 0.79 | HTT (0.42) | ACHEHTTMAOBALDH1A1POLB | |
| SCHEMBL7769630 | 0.79 | ALDH1A1 (0.37) | ACHEHTTALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL11970037 | 0.77 | EPHX1 (0.59) | ACHE | |
| SCHEMBL12096945 | 0.77 | EPHX1 (0.59) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1077110-C | 13-substituted milbemycin 5-oxime derivatives their preparation and their use against insects and other pests | SANKYO CO (JP) | 2002-01-02 | — | — | CN | disclosed |
| EP-0765879-B1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO CO (JP) | 2001-02-14 | — | — | EP | disclosed |
| US-5861429-A | MITICIDES AND ANTHELMINTICS | SANKYO COMPANY, LIMITED (JP) | 1999-01-19 | — | — | US | disclosed |
| CN-1153177-A | 13-substituted milbemycin 5-oxime derivatives their preparation and their use against insects and other pests | SANKYO CO (JP) | 1997-07-02 | — | — | CN | disclosed |
| EP-0765879-A1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO COMPANY LIMITED (JP) | 1997-04-02 | — | — | EP | disclosed |