SCHEMBL7621149

SCHEMBL7621149

CCc1ccc(S(=O)(=O)NC(=O)c2ccc(NC(=O)Nc3ccccc3)cc2)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.63
MAPT P10636 1/20 0.63
LMNA P02545 4/20 0.54
GHSR Q92847 2/20 0.53
LIMK2 P53671 1/20 0.52
BCL2L1 Q07817 1/20 0.51
MCL1 Q07820 1/20 0.51
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
CA1 P00915 2/20 0.50
CA2 P00918 2/20 0.50
CA9 Q16790 2/20 0.50
FLT1 P17948 1/20 0.50
FLT4 P35916 1/20 0.50
KDR P35968 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
NPC1 O15118 1/20 0.49
HPGD P15428 1/20 0.49
HTT P42858 1/20 0.49
CA12 O43570 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7776163 0.90 ALDH1A1 (0.58) ALDH1A1MAPTLMNAGHSRBCL2L1
SCHEMBL7641936 0.88 ALDH1A1 (0.52) ALDH1A1MAPTLMNAGHSRLIMK2
SCHEMBL6295675 0.87 SIRT1 (0.60) ALDH1A1MAPTLMNAMEN1KMT2A
SCHEMBL6295620 0.87 MEN1 (0.65) LMNAMEN1KMT2ACA1CA2
SCHEMBL7774521 0.86 LMNA (0.74) ALDH1A1MAPTLMNAMEN1KMT2A
SCHEMBL7647250 0.86 LMNA (0.74) ALDH1A1MAPTLMNAMEN1KMT2A
SCHEMBL7776051 0.84 NPC1 (0.57) ALDH1A1MAPTLMNABCL2L1MCL1
SCHEMBL7770070 0.84 NPC1 (0.57) ALDH1A1MAPTLMNABCL2L1MCL1
SCHEMBL7776312 0.84 MAOA (0.61) ALDH1A1LMNABCL2L1MCL1MEN1
SCHEMBL7770072 0.84 MAOA (0.61) ALDH1A1LMNABCL2L1MCL1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0863022-B1 Thermally sensitive recording medium JUJO PAPER CO LTD (JP) 2002-09-18 EP disclosed
EP-0788889-B1 A thermal sensitive recording sheet JUJO PAPER CO LTD (JP) 2001-08-08 EP disclosed
US-6028030-A CONTAINING AN IMAGE PRESERVATIVE/STABILIZER POLYUREA IN THE THERMAL COLOR DEVELOPING LAYER CONTAINING DYE PRECURSOR NIPPON PAPER INDUSTRIE CO., LTD. (JP) 2000-02-22 US disclosed
EP-0863022-A1 Thermally sensitive recording medium NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1998-09-09 EP disclosed
EP-0788889-A2 A thermal sensitive recording sheet NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1997-08-13 EP disclosed