SCHEMBL7770071

SCHEMBL7770071

Cc1ccc(SNC(=O)Nc2ccc(C(=O)NS(=O)(=O)c3ccc([N+](=O)[O-])cc3)cc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FLT1 P17948 1/20 0.54
FLT4 P35916 1/20 0.54
KDR P35968 1/20 0.54
GAA P10253 3/20 0.51
POLB P06746 2/20 0.51
MMP9 P14780 3/20 0.51
MMP1 P03956 2/20 0.51
MMP2 P08253 2/20 0.51
MMP8 P22894 2/20 0.51
MMP13 P45452 2/20 0.51
CA1 P00915 2/20 0.49
CA2 P00918 2/20 0.49
CA9 Q16790 2/20 0.49
MAPT P10636 2/20 0.49
ALDH1A1 P00352 2/20 0.49
HPGD P15428 2/20 0.49
ATM Q13315 1/20 0.48
TP53 P04637 1/20 0.46
CA12 O43570 1/20 0.46
CA4 P22748 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7774805 0.89 FLT1 (0.63) FLT1FLT4KDRGAAPOLB
SCHEMBL7643073 0.86 LMNA (0.60) FLT1FLT4KDRGAAMMP9
SCHEMBL8767411 0.85 FLT1 (0.51) FLT1FLT4KDRGAAPOLB
SCHEMBL7770073 0.84 HSD17B10 (0.57) GAAPOLBMMP9MMP2CA1
SCHEMBL8627793 0.83 FLT1 (0.74) FLT1FLT4KDRGAAPOLB
SCHEMBL8913272 0.83 ALDH1A1 (0.64) FLT1FLT4KDRGAAPOLB
SCHEMBL8767632 0.82 LMNA (0.51) GAACA1CA2CA9ALDH1A1
SCHEMBL9468106 0.81 FLT1 (0.64) FLT1FLT4KDRGAAPOLB
SCHEMBL16387045 0.81 CA12 (0.68) GAAPOLBMMP9MMP1MMP2
SCHEMBL7776284 0.80 MEN1 (0.66) FLT1FLT4KDRGAACA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0788889-B1 A thermal sensitive recording sheet JUJO PAPER CO LTD (JP) 2001-08-08 EP disclosed
EP-0788889-A2 A thermal sensitive recording sheet NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1997-08-13 EP disclosed