SCHEMBL7770073

SCHEMBL7770073

COc1ccc(S(=O)(=O)NC(=O)c2ccc(NC(=O)NSc3ccc(C)cc3)cc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.57
NPC1 O15118 1/20 0.54
RAB9A P51151 1/20 0.54
LMNA P02545 2/20 0.51
ALDH1A1 P00352 2/20 0.47
MAPT P10636 2/20 0.47
CYP1A2 P05177 1/20 0.47
CYP3A4 P08684 1/20 0.47
CYP2C9 P11712 1/20 0.47
CYP2C19 P33261 1/20 0.47
EGFR P00533 1/20 0.47
TP53 P04637 2/20 0.47
CA12 O43570 1/20 0.47
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
CA4 P22748 1/20 0.47
CA6 P23280 1/20 0.47
CA5A P35218 1/20 0.47
CA7 P43166 1/20 0.47
CA9 Q16790 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7776157 0.91 HSD17B10 (0.58) HSD17B10NPC1RAB9ALMNAMAPT
SCHEMBL8657117 0.89 HSD17B10 (0.67) HSD17B10NPC1RAB9ALMNAALDH1A1
SCHEMBL7643073 0.87 LMNA (0.60) NPC1RAB9ALMNAALDH1A1MAPT
SCHEMBL8768261 0.87 HSD17B10 (0.54) HSD17B10NPC1RAB9ALMNAMMP2
SCHEMBL7770071 0.84 FLT1 (0.54) NPC1LMNAALDH1A1MAPTCYP3A4
SCHEMBL8767632 0.84 LMNA (0.51) NPC1RAB9ALMNAALDH1A1TP53
SCHEMBL795861 0.83 ALDH1A1 (0.64) HSD17B10NPC1RAB9AALDH1A1MAPT
SCHEMBL8659568 0.82 HSD17B10 (0.65) HSD17B10NPC1RAB9ALMNAALDH1A1
SCHEMBL5187356 0.81 CA12 (0.70) HSD17B10NPC1RAB9ALMNAALDH1A1
SCHEMBL7776284 0.80 MEN1 (0.66) NPC1RAB9ALMNAALDH1A1CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0788889-B1 A thermal sensitive recording sheet JUJO PAPER CO LTD (JP) 2001-08-08 EP disclosed
EP-0788889-A2 A thermal sensitive recording sheet NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1997-08-13 EP disclosed