Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 14/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.50 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7771611 | 0.94 | ACHE (0.48) | ACHEHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL7769261 | 0.88 | ACHE (0.44) | ACHEHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL10778878 | 0.84 | ACHE (0.53) | ACHEHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL21068069 | 0.83 | ACHE (0.61) | ACHEHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL7570219 | 0.83 | ACHE (0.61) | ACHEHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL25349245 | 0.82 | CYP1A2 (0.53) | ACHEHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL7385877 | 0.82 | ACHE (0.52) | ACHEHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL7770088 | 0.82 | ACHE (0.52) | ACHEHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL15549930 | 0.82 | HTT (0.56) | ACHEHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL7769323 | 0.82 | EPHX1 (0.55) | ACHEKMT2AEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0765879-B1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO CO (JP) | 2001-02-14 | — | — | EP | disclosed |
| US-5861429-A | MITICIDES AND ANTHELMINTICS | SANKYO COMPANY, LIMITED (JP) | 1999-01-19 | — | — | US | disclosed |
| EP-0765879-A1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO COMPANY LIMITED (JP) | 1997-04-02 | — | — | EP | disclosed |