Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.55 |
| ▸ | ACHE | P22303 | 8/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7769387 | 0.94 | EPHX1 (0.59) | EPHX1ACHETSHRTDP1KDM4E | |
| SCHEMBL7771583 | 0.92 | EPHX1 (0.62) | EPHX1ACHETDP1KDM4EMAPK1 | |
| SCHEMBL7770935 | 0.92 | EPHX1 (0.62) | EPHX1ACHETDP1KDM4EMAPK1 | |
| SCHEMBL7765972 | 0.86 | EPHX1 (0.48) | EPHX1ACHETSHRMEN1KMT2A | |
| SCHEMBL7770082 | 0.82 | ACHE (0.50) | EPHX1ACHEKMT2A | |
| SCHEMBL7252127 | 0.81 | EPHX1 (0.77) | EPHX1ACHETSHRTDP1KDM4E | |
| SCHEMBL14433357 | 0.81 | EPHX1 (0.70) | EPHX1ACHETSHRTDP1KDM4E | |
| SCHEMBL12972297 | 0.80 | EPHX1 (0.57) | EPHX1ACHETSHRTDP1KDM4E | |
| SCHEMBL21538522 | 0.80 | TSHR (0.61) | EPHX1ACHETSHR | |
| SCHEMBL628018 | 0.80 | EPHX1 (0.57) | EPHX1ACHETSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0765879-B1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO CO (JP) | 2001-02-14 | — | — | EP | disclosed |
| US-5861429-A | MITICIDES AND ANTHELMINTICS | SANKYO COMPANY, LIMITED (JP) | 1999-01-19 | — | — | US | disclosed |
| EP-0765879-A1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO COMPANY LIMITED (JP) | 1997-04-02 | — | — | EP | disclosed |