Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 1/20 | 0.53 |
| ▸ | IAPP | P10997 | 4/20 | 0.47 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.46 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.46 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.46 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.46 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.46 |
| ▸ | PGK1 | P00558 | 2/20 | 0.45 |
| ▸ | PGK2 | P07205 | 2/20 | 0.45 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1585388 | 0.98 | ACP3 (0.52) | ACP3IAPPGRIN2DGRIN3BGRIN1 | |
| Phosphoric Acid SCHEMBL466514 | 0.83 | GABRA1 (0.64) | IAPPADAMTS4ALDH1A1EGFRCA1 | |
| SCHEMBL915357 | 0.83 | ACP3 (0.57) | ACP3GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL14769204 | 0.80 | IAPP (0.53) | IAPPADAMTS4ALDH1A1EGFRCA1 | |
| SCHEMBL915456 | 0.80 | ACP3 (0.65) | ACP3GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL1585391 | 0.80 | IAPP (0.44) | IAPPADAMTS4ALDH1A1EGFRCA1 | |
| SCHEMBL27609859 | 0.80 | ACP3 (0.50) | ACP3GRIN2DGRIN3BGRIN1GRIN2A | |
| Pyrogallol SCHEMBL27844566 | 0.79 | ALDH1A1 (0.71) | IAPPADAMTS4ALDH1A1EGFRCA1 | |
| Pyrogallol SCHEMBL5606364 | 0.79 | ALDH1A1 (0.71) | IAPPADAMTS4ALDH1A1EGFRCA1 | |
| SCHEMBL1585364 | 0.79 | IAPP (0.51) | IAPPADAMTS4ALDH1A1EGFRCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0690064-B1 | Process for preparing sterically hindered hydroxybenzylphosphonates | CIBA SC HOLDING AG (CH) | 2001-07-11 | — | — | EP | claimed |
| US-20130065857-A1 | NOVEL DXR INHIBITORS FOR ANTIMICROBIAL THERAPY | BAYLOR COLLEGE OF MEDICINE (US) | 2013-03-14 | — | — | US | disclosed |
| US-20130065857-A1 | NOVEL DXR INHIBITORS FOR ANTIMICROBIAL THERAPY | BAYLOR COLLEGE OF MEDICINE (US) | 2013-03-14 | — | — | US | disclosed |
| EP-0690064-B1 | Process for preparing sterically hindered hydroxybenzylphosphonates | CIBA SC HOLDING AG (CH) | 2001-07-11 | — | — | EP | disclosed |
| EP-0507738-B1 | Process for preparing sterically mindered hydroxybenzylphosphonates | CIBA GEIGY AG (CH) | 1996-07-17 | — | — | EP | disclosed |
| EP-0690064-A1 | Process for preparing sterically hindered hydroxybenzylphosphonates | CIBA-GEIGY AG (CH) | 1996-01-03 | — | — | EP | disclosed |
| EP-0507738-A2 | Process for preparing sterically mindered hydroxybenzylphosphonates | CIBA-GEIGY AG (CH) | 1992-10-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130065857-A1 | NOVEL DXR INHIBITORS FOR ANTIMICROBIAL THERAPY | DDX18, FPR1, DCXR | ACP3 4134/4885IAPP 4764/4885GRIN2D 3237/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.