Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL777790 | 0.87 | SRC (0.45) | SMN1; SMN2RAB9ASRCPKMALDH1A1 | |
| SCHEMBL5678305 | 0.82 | SRC (0.40) | SMN1; SMN2CYP3A4CYP1A2CYP2C19POLB | |
| SCHEMBL8349055 | 0.72 | SRC (0.45) | RAB9ASRCALDH1A1 | |
| SCHEMBL31012115 | 0.70 | KMO (0.49) | — | |
| SCHEMBL29402836 | 0.70 | KMO (0.49) | — | |
| SCHEMBL1787743 | 0.70 | KMO (0.49) | — | |
| SCHEMBL779521 | 0.70 | LMNA (0.41) | SMN1; SMN2CYP3A4CYP1A2CYP2C19POLB | |
| SCHEMBL11734526 | 0.69 | GPR84 (0.51) | SMN1; SMN2CYP1A2RAB9AHPGDFAAH | |
| SCHEMBL11340668 | 0.69 | SRC (0.42) | SMN1; SMN2RAB9ASRCPKMALDH1A1 | |
| SCHEMBL11658493 | 0.69 | SRC (0.52) | SMN1; SMN2CYP2C19RAB9ASRCPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1112313-A1 | HALOGEN-FREE FLAME RETARDANT THERMOPLASTIC POLYMER COMPOSITIONS | ALBEMARLE CORPORATION (US) | 2001-07-04 | — | — | EP | disclosed |
| WO-2000017268-A1 | HALOGEN-FREE FLAME RETARDANT THERMOPLASTIC POLYMER COMPOSITIONS | ALBEMARLE CORPORATION (US) | 2000-03-30 | — | — | WO | disclosed |