SCHEMBL7770677

SCHEMBL7770677

CCC(C)[SiH](O[SiH](C(C)CC)C(C)CC)C(C)CC

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4768441 0.78 TSHR (0.30) TSHR
SCHEMBL22534508 0.75
SCHEMBL28310426 0.75
SCHEMBL1313494 0.75 LMNA (0.32)
SCHEMBL15914761 0.71
SCHEMBL5711130 0.71
SCHEMBL7770683 0.71 TSHR (0.30) TSHR
SCHEMBL1572908 0.69
SCHEMBL7770128 0.69 LMNA (0.32)
SCHEMBL4622908 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3784718-B1 PROCESS FOR THE PREPARATION OF HYDROXYL-FUNCTIONALIZED POLYETHERPOLYSILOXANE BLOCK COPOLYMERS HENKEL AG & CO KGAA (DE) 2024-06-26 EP disclosed
US-20220411634-A1 SILICONE FORMULATION WITH HIGH TEMPERATURE STABILITY AND CLARITY HENKEL AG & CO. KGAA (DE) 2022-12-29 US disclosed
EP-4108726-A1 SILICONE FORMULATION WITH HIGH TEMPERATURE STABILITY AND CLARITY Henkel AG & Co. KGaA (DE) 2022-12-28 EP disclosed
US-11326027-B2 Process for the preparation of hydroxyl-functionalized polysiloxanes HENKEL AG & CO. KGAA (DE) 2022-05-10 US disclosed
CN-114096590-A UV and/or thermally curable silicone-based materials and formulations 汉高知识产权控股有限责任公司 2022-02-25 CN disclosed
EP-3953412-A1 UV AND/OR HEAT CURABLE SILICONE BASED MATERIALS AND FORMULATIONS Henkel IP & Holding GmbH (DE) 2022-02-16 EP disclosed
US-20220025180-A1 UV AND/OR HEAT CURABLE SILICONE BASED MATERIALS AND FORMULATIONS HENKEL AG & CO. KGAA (DE) 2022-01-27 US disclosed
EP-3336129-B1 PROCESS FOR THE PREPARATION OF HYDROXYL-FUNCTIONALIZED POLYSILOXANES HENKEL AG & CO KGAA (DE) 2021-03-17 EP disclosed
US-20210040269-A1 PROCESS FOR THE PREPARATION OF HYDROXYL-FUNCTIONALIZED POLYETHER-POLYSILOXANE BLOCK COPOLYMERS HENKEL AG & CO KGAA (DE) 2021-02-11 US disclosed
CN-112004862-A Process for preparing hydroxy-functionalized polyether-polysiloxane block copolymers 汉高股份有限及两合公司 2020-11-27 CN disclosed
US-20190322808-A1 Process for the Preparation of Hydroxyl-Functionalized Polysiloxanes LEIBNIZ-INSTITUT FUR KATALYSE E.V. (LIKAT) (DE) 2019-10-24 US disclosed
EP-3336129-A1 PROCESS FOR THE PREPARATION OF HYDROXYL-FUNCTIONALIZED POLYSILOXANES Henkel AG & Co. KGaA (DE) 2018-06-20 EP disclosed
US-9970103-B2 Film deposition material, sealing film using the same and use thereof TOSOH CORPORATION (JP) 2018-05-15 US disclosed
CN-103781937-B Filmogen, the diaphragm seal using the filmogen, and application thereof 东曹株式会社 2017-05-31 CN disclosed
US-20160326642-A1 FILM DEPOSITION MATERIAL, SEALING FILM USING THE SAME AND USE THEREOF TOSOH CORPORATION (JP) 2016-11-10 US disclosed
US-20140219903-A1 FILM DEPOSITION MATERIAL, SEALING FILM USING THE SAME AND USE THEREOF TOSOH CORPORATION (JP) 2014-08-07 US disclosed
EP-1114824-B1 Process for preparing 1,3-dihalo-1,1,3,3-tetraorgano disilioxanes WACKER CHEMIE GMBH (DE) 2001-12-12 EP disclosed
US-6284907-B1 REACTING HYDROGEN HALIDE WITH THE CORRESPONDING 1,3-DIHYDRO-1,1,3,3-TETRA(ORGANYL)DISILOXANES; CATALYST SELECTED FROM TRANSITION METALS OF THE 8TH SUBGROUP OF THE PERIODIC TABLE OF THE ELEMENTS, OR COMPOUNDS OR COMPLEXES WACKER-CHEMIE GMBH (DE) 2001-09-04 US disclosed
EP-1114824-A1 Process for preparing 1,3-dihalo-1,1,3,3-tetraorgano disilioxanes Wacker-Chemie GmbH (DE) 2001-07-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11326027-B2 Process for the preparation of hydroxyl-functionalized polysiloxanes C9, HACL2, ADH1C TSHR 1408/4885
US-20190322808-A1 Process for the Preparation of Hydroxyl-Functionalized Polysiloxanes C9, HACL2, ADH1C TSHR 1408/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.