Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
| ▸ | GALR3 | O60755 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16029585 | 0.82 | LMNA (0.34) | TSHRCHRM2CHRM4CHRM1MAPT | |
| SCHEMBL15710851 | 0.82 | TSHR (0.30) | TSHR | |
| SCHEMBL4268647 | 0.81 | TSHR (0.36) | TSHR | |
| SCHEMBL100240 | 0.79 | TSHR (0.41) | TSHRCHRM2CHRM4CHRM1TBXA2R | |
| SCHEMBL4276183 | 0.79 | TSHR (0.37) | TSHR | |
| SCHEMBL8827532 | 0.78 | TSHR (0.39) | TSHRCHRM2CHRM4CHRM1TBXA2R | |
| SCHEMBL31168253 | 0.76 | ALDH1A1 (0.33) | TSHR | |
| SCHEMBL28050657 | 0.75 | TSHR (0.50) | TSHRCHRM2CHRM4CHRM1TBXA2R | |
| SCHEMBL31146732 | 0.75 | TDP1 (0.35) | TSHR | |
| SCHEMBL32679655 | 0.73 | TSHR (0.39) | TSHRCHRM2CHRM4CHRM1TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0837867-B1 | MODIFIED ALPHA-D-Glcp-(1-2)-ALPHA-D-Glcp-(1-3)-ALPHA-D-Glcp-ANALOGUES | ALBERTA RES COUNCIL (CA) | 2001-08-16 | — | — | EP | disclosed |
| US-5929037-A | GLUCOSIDASE I INHIBITORS | ALBERTA RESEARCH COUNCIL (CA) | 1999-07-27 | — | — | US | disclosed |
| EP-0837867-A1 | MODIFIED $g(a)-D-Glcp-(1-2)-$g(a)-D-Glcp-(1-3)-$g(a)-D-Glcp-ANALOGUES | ALBERTA RESEARCH COUNCIL (CA) | 1998-04-29 | — | — | EP | disclosed |
| WO-1996040700-A1 | MODIFIED α-D-Glcp-(1-2)-α-D-Glcp-(1-3)-α-D-Glcp-ANALOGUES | ALBERTA RESEARCH COUNCIL (CA) | 1996-12-19 | — | — | WO | disclosed |