Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
| ▸ | GALR3 | O60755 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32679655 | 0.86 | TSHR (0.39) | TSHRTDP1CHRM2CHRM4CHRM1 | |
| SCHEMBL31612302 | 0.85 | TSHR (0.42) | TSHRTDP1CHRM2CHRM4CHRM1 | |
| SCHEMBL30473268 | 0.81 | TDP1 (0.34) | TSHRTDP1 | |
| SCHEMBL7770757 | 0.79 | TSHR (0.41) | TSHRCHRM2CHRM4CHRM1TBXA2R | |
| SCHEMBL9090174 | 0.78 | TDP1 (0.47) | TDP1MAPTSMN1; SMN2 | |
| SCHEMBL8827532 | 0.78 | TSHR (0.39) | TSHRTDP1CHRM2CHRM4CHRM1 | |
| SCHEMBL5167248 | 0.77 | TDP1 (0.64) | TDP1MAPTSMN1; SMN2 | |
| SCHEMBL10506819 | 0.77 | TSHR (0.42) | TSHRTDP1CHRM2CHRM4CHRM1 | |
| SCHEMBL10511706 | 0.77 | TSHR (0.42) | TSHRTDP1CHRM2CHRM4CHRM1 | |
| SCHEMBL10510282 | 0.77 | TSHR (0.42) | TSHRTDP1CHRM2CHRM4CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8273955-B2 | Spontaneous nodulation in plants | AARHUS UNIVERSITET (DK) | 2012-09-25 | — | — | US | disclosed |
| EP-2044201-B1 | A MUTANT HISTIDINE KINASE THAT CONFERS SPONTANEOUS NODULATION IN PLANTS | PLANT BIOSCIENCE LTD (GB) | 2012-05-23 | — | — | EP | disclosed |
| WO-2012028673-A1 | SPONTANEOUS ORGANOGENESIS IN PLANTS | LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN (DE) | 2012-03-08 | — | — | WO | disclosed |
| EP-2426204-A1 | Spontaneous nodule organogenesis in plants | Ludwig-Maximilians-Universität München (DE) | 2012-03-07 | — | — | EP | disclosed |
| EP-1902133-B1 | SPONTANEOUS NODULATION IN PLANTS | UNIV AARHUS (DK) | 2012-02-22 | — | — | EP | disclosed |
| US-20110078814-A1 | SPONTANEOUS NODULATION IN PLANTS | AARHUS UNIVERSITY | 2011-03-31 | — | — | US | disclosed |
| US-20100031388-A1 | MUTANT HISTIDINE KINASE THAT CONFERS SPONTANEOUS NODULATION IN PLANTS | PLANT BIOSCIENCES LTD. (GB) | 2010-02-04 | — | — | US | disclosed |
| EP-2044201-A1 | A MUTANT HISTIDINE KINASE THAT CONFERS SPONTANEOUS NODULATION IN PLANTS | Plant Bioscience Limited (GB) | 2009-04-08 | — | — | EP | disclosed |
| EP-1902133-A2 | SPONTANEOUS NODULATION IN PLANTS | Aarhus Universitet (DK) | 2008-03-26 | — | — | EP | disclosed |
| WO-2008009287-A1 | A MUTANT HISTIDINE KINASE THAT CONFERS SPONTANEOUS NODULATION IN PLANTS | PLANT BIOSCIENCES LTD. (GB) | 2008-01-24 | — | — | WO | disclosed |
| WO-2007006318-A2 | SPONTANEOUS NODULATION IN PLANTS | AARHUS UNIVERSITET (DK) | 2007-01-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100031388-A1 | MUTANT HISTIDINE KINASE THAT CONFERS SPONTANEOUS NODULATION IN PLANTS | IP6K2, BMP2K, HIPK2 | TSHR 2224/4885TDP1 4723/4885CHRM2 1225/4885 |
| US-20110078814-A1 | SPONTANEOUS NODULATION IN PLANTS | PIP5K1B, HINT1, NT5C | TSHR 3003/4885TDP1 4352/4885CHRM2 1380/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.