Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7992862 | 0.82 | TDP1 (0.40) | TDP1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL1227082 | 0.76 | TDP1 (0.46) | TDP1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL27706260 | 0.76 | TDP1 (0.43) | TDP1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL2367602 | 0.75 | ALDH1A1 (0.41) | TDP1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL8882964 | 0.75 | ALDH1A1 (0.41) | TDP1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL4862797 | 0.74 | FFAR3 (0.43) | TDP1TSHRFFAR3ALDH1A1 | |
| SCHEMBL9638448 | 0.73 | RNPEP (0.34) | TDP1CHRM1AKR1A1CHRM3HTR2A | |
| Hydrochloric Acid SCHEMBL9761260 | 0.72 | FFAR3 (0.40) | TDP1TSHRFFAR3ALDH1A1 | |
| SCHEMBL1604267 | 0.72 | TDP1 (0.50) | TDP1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL13761133 | 0.72 | TDP1 (0.50) | TDP1CHRM1AKR1A1CHRM3HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0755927-B1 | DIMETHYLFURANCARBOXANILIDE DERIVATIVE | SANKYO CO (JP) | 2001-07-18 | — | — | EP | disclosed |