Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNPEP | Q9H4A4 | 2/20 | 0.34 |
| ▸ | MME | P08473 | 2/20 | 0.34 |
| ▸ | ACE | P12821 | 2/20 | 0.34 |
| ▸ | CPA1 | P15085 | 2/20 | 0.34 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.33 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9637603 | 0.82 | CHRM1 (0.44) | RNPEPTDP1MAPTCA2MAPK1 | |
| SCHEMBL9637645 | 0.79 | CA2 (0.45) | ACE2TDP1MAPTCA2MAPK1 | |
| SCHEMBL9637742 | 0.77 | GPR84 (0.47) | ACE2MAPTCA2MAPK1SLC1A2 | |
| SCHEMBL9638470 | 0.76 | GPR84 (0.50) | ACE2MAPTCA2SLC1A2SLC1A1 | |
| SCHEMBL2367602 | 0.73 | ALDH1A1 (0.41) | RNPEPMMEACECPA1ACE2 | |
| SCHEMBL7770762 | 0.73 | TDP1 (0.39) | TDP1ALDH1A1CA2MAPK1CHRM1 | |
| SCHEMBL8882964 | 0.73 | ALDH1A1 (0.41) | RNPEPMMEACECPA1ACE2 | |
| SCHEMBL10573309 | 0.73 | SLC1A3 (0.31) | TDP1CA2MAPK1CHRM1AKR1A1 | |
| SCHEMBL4862797 | 0.73 | FFAR3 (0.43) | TDP1HPGDHSD17B10KDM4EMAPT | |
| SCHEMBL9637727 | 0.72 | RNPEP (0.39) | RNPEPACETDP1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0367508-B1 | MERCAPTOALKYL ACETOACETATES, USE THEREOF AND A PROCESS FOR THE PREPARATION OF MERCAPTOALKYL ACETOACETATES | ROHM AND HAAS COMPANY (US) | 1992-07-22 | — | — | EP | claimed |
| EP-0367508-A1 | Mercaptoalkyl acetoacetates, use thereof and a process for the preparation of mercaptoalkyl acetoacetates | ROHM AND HAAS COMPANY (US) | 1990-05-09 | — | — | EP | claimed |