Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | PDE5A | O76074 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7776122 | 1.00 | RIPK1 (0.43) | RIPK1TSHRPKMPDE5AALDH1A1 | |
| SCHEMBL7776125 | 0.84 | EPHX1 (0.53) | TSHRALDH1A1TP53CYP2C19EPHX1 | |
| SCHEMBL30349443 | 0.84 | TSHR (0.45) | TSHRALDH1A1L3MBTL1OPRK1POLB | |
| SCHEMBL30349638 | 0.84 | TSHR (0.45) | TSHRALDH1A1L3MBTL1OPRK1POLB | |
| SCHEMBL3207241 | 0.84 | TSHR (0.45) | TSHRALDH1A1L3MBTL1OPRK1POLB | |
| SCHEMBL3207235 | 0.84 | TSHR (0.45) | TSHRALDH1A1L3MBTL1OPRK1POLB | |
| SCHEMBL7772636 | 0.82 | TSHR (0.61) | RIPK1TSHRALDH1A1TP53L3MBTL1 | |
| SCHEMBL16303826 | 0.82 | TSHR (0.61) | RIPK1TSHRALDH1A1TP53L3MBTL1 | |
| SCHEMBL7770452 | 0.82 | TSHR (0.61) | RIPK1TSHRALDH1A1TP53L3MBTL1 | |
| SCHEMBL9488854 | 0.82 | TSHR (0.61) | RIPK1TSHRALDH1A1TP53L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1127885-A2 | Optically active epoxypropionate derivatives, intermediates, and processes for their production | Tosoh Corporation (JP) | 2001-08-29 | — | — | EP | disclosed |