Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7571849 | 1.00 | CDK2 (0.33) | CDK2MEN1MAPTKMT2AKDM4E | |
| SCHEMBL1389034 | 0.91 | EZH2 (0.33) | MAPT | |
| SCHEMBL1389035 | 0.91 | EZH2 (0.33) | MAPT | |
| SCHEMBL31238363 | 0.82 | MAPT (0.48) | CDK2MEN1MAPTKMT2AKDM4E | |
| SCHEMBL7514650 | 0.78 | CDK2 (0.34) | CDK2 | |
| SCHEMBL7514647 | 0.78 | CDK2 (0.34) | CDK2 | |
| SCHEMBL31238321 | 0.78 | GAA (0.33) | MEN1MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL19452944 | 0.77 | ALDH1A1 (0.39) | MEN1MAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL7581044 | 0.75 | CDK2 (0.42) | CDK2MEN1MAPTKMT2AKDM4E | |
| SCHEMBL7575050 | 0.74 | ALDH1A1 (0.31) | CDK2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0825983-B1 | PROCESS FOR THE PREPARATION OF 2,2'-BIPYRROLYL-PYRROMETHENE (PRODIGIOSINS) DERIVATIVES | PHARMACIA & UPJOHN SPA (IT) | 2001-08-29 | — | — | EP | claimed |