Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | CD40 | P25942 | 1/20 | 0.52 |
| ▸ | CD40LG | P29965 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.51 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.51 |
| ▸ | ENPP2 | Q13822 | 10/20 | 0.50 |
| ▸ | NSD2 | O96028 | 1/20 | 0.50 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.50 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.50 |
| ▸ | CASP6 | P55212 | 1/20 | 0.50 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | DNASE1L3 | Q13609 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8070763 | 1.00 | PHLPP2 (0.54) | PHLPP2MEN1THRBKMT2ATDP1 | |
| SCHEMBL10351775 | 0.95 | MEN1 (0.56) | PHLPP2MEN1THRBKMT2ATDP1 | |
| SCHEMBL8035550 | 0.93 | PHLPP2 (0.57) | PHLPP2MEN1THRBKMT2ATDP1 | |
| SCHEMBL8972293 | 0.92 | PHLPP2 (0.53) | PHLPP2MEN1THRBKMT2ATDP1 | |
| SCHEMBL8971759 | 0.92 | PRMT1 (0.52) | PHLPP2MEN1THRBKMT2ATDP1 | |
| SCHEMBL10393298 | 0.90 | ALDH1A1 (0.52) | PHLPP2MEN1THRBKMT2ATDP1 | |
| SCHEMBL14493395 | 0.90 | ENPP2 (0.59) | PHLPP2MEN1THRBKMT2ATDP1 | |
| SCHEMBL10618136 | 0.90 | CD40 (0.54) | PHLPP2MEN1THRBKMT2ATDP1 | |
| SCHEMBL9331711 | 0.88 | MEN1 (0.54) | PHLPP2MEN1THRBKMT2ATDP1 | |
| SCHEMBL9331723 | 0.88 | MEN1 (0.54) | PHLPP2MEN1THRBKMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0748850-B1 | Dyestuffs, process for their preparation and their use | CIBA SC HOLDING AG (CH) | 2001-07-04 | — | — | EP | disclosed |
| US-5931975-A | TRIAZINE REACTIVE DYES | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1999-08-03 | — | — | US | disclosed |
| EP-0748850-A1 | Dyestuffs, process for their preparation and their use | CIBA-GEIGY AG (CH) | 1996-12-18 | — | — | EP | disclosed |
| EP-0625551-A1 | Mixtures of dyes, process for their preparation and the use thereof | CIBA-GEIGY AG (CH) | 1994-11-23 | — | — | EP | disclosed |