SCHEMBL7771198

SCHEMBL7771198

Oc1cccc(C(c2ccccc2)c2ccccc2)c1O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 5/20 0.46
ALDH1A1 P00352 4/20 0.46
TDP1 Q9NUW8 4/20 0.46
ALOX15 P16050 3/20 0.46
RECQL P46063 3/20 0.46
HSD17B10 Q99714 3/20 0.46
CA2 P00918 3/20 0.46
LMNA P02545 3/20 0.46
CA1 P00915 2/20 0.46
EGFR P00533 2/20 0.46
FYN P06241 2/20 0.46
MMP9 P14780 2/20 0.46
ADAMTS4 O75173 1/20 0.46
MMP2 P08253 1/20 0.46
MMP8 P22894 1/20 0.46
CA6 P23280 1/20 0.46
CDK2 P24941 1/20 0.46
MMP12 P39900 1/20 0.46
ADAMTS5 Q9UNA0 1/20 0.46
TYR P14679 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19806914 0.96 HPGD (0.46) HPGDALDH1A1TDP1ALOX15RECQL
SCHEMBL23082197 0.86 LMNA (0.50) HPGDALDH1A1TDP1ALOX15RECQL
SCHEMBL982045 0.84 GABRA1 (0.52) HPGDALDH1A1TDP1ALOX15RECQL
SCHEMBL6744407 0.83 TYR (0.40) HPGDALDH1A1TDP1ALOX15RECQL
SCHEMBL7160136 0.82 LMNA (0.50) HPGDALDH1A1TDP1ALOX15RECQL
SCHEMBL9811611 0.82 LMNA (0.50) HPGDALDH1A1TDP1ALOX15RECQL
SCHEMBL23082067 0.81 LMNA (0.44) HPGDALDH1A1TDP1ALOX15RECQL
SCHEMBL1955258 0.81 KMT2A (0.42) HPGDALDH1A1TDP1ALOX15RECQL
SCHEMBL51106 0.79 GABRA1 (0.52) HPGDALDH1A1TDP1ALOX15RECQL
SCHEMBL1426621 0.79 TYR (0.55) HPGDALDH1A1TDP1ALOX15RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100469826-C Phenols with antibacterial activity and compositions of inorganic material CIBA SC HOLDING AG (CH) 2009-03-18 CN disclosed
CN-1344758-A Phenols with antibacterial activity and compositions of inorganic material CIBA SC HOLDING AG (CH) 2002-04-17 CN disclosed
EP-0759045-B1 CROSS-LINKED OR CROSS-LINKABLE OPTICAL POLYCARBONATES AND OPTICAL COMPONENTS COMPRISING SAID OPTICAL POLYCARBONATES JDS UNIPHASE PHOTONICS C V (NL) 2001-07-25 EP disclosed
EP-0835469-B1 AT LEAST PENTA-LAYERED OPTICAL DEVICE JDS FITEL PHOTONICS C V (NL) 2000-08-30 EP disclosed
US-5908916-A AROMATIC POLYCARBONATES AKZO NOBEL N.V. (NL) 1999-06-01 US disclosed
US-5861976-A At Least penta-layered optical device AKZO NOBEL NV (NL) 1999-01-19 US disclosed
CN-1189221-A At least penta-layered optical device AKZO NOBEL NV (NL) 1998-07-29 CN disclosed
EP-0835469-A1 AT LEAST PENTA-LAYERED OPTICAL DEVICE Akzo Nobel N.V. (NL) 1998-04-15 EP disclosed
EP-0759045-A1 CROSS-LINKED OR CROSS-LINKABLE OPTICAL POLYCARBONATES AND OPTICAL COMPONENTS COMPRISING SAID OPTICAL POLYCARBONATES Akzo Nobel N.V. (NL) 1997-02-26 EP disclosed
WO-1997001782-A1 AT LEAST PENTA-LAYERED OPTICAL DEVICE AKZO NOBEL N.V. (NL) 1997-01-16 WO disclosed
WO-1996028493-A1 CROSS-LINKED OR CROSS-LINKABLE OPTICAL POLYCARBONATES AND OPTICAL COMPONENTS COMPRISING SAID OPTICAL POLYCARBONATES AKZO NOBEL N.V. (NL) 1996-09-19 WO disclosed